Lifan Chen

TransformerCPI: improving compound–protein interaction prediction by sequence-based deep learning with self-attention mechanism and label reversal experiments

Lifan Chen, Xiaoqin Tan, Dingyan Wang et al. · Bioinformatics · 2020 · 515 citations · Full text

Sequence-based drug design as a concept in computational drug design

Lifan Chen, Zisheng Fan, Jie Chang et al. · Nature Communications · 2023 · 107 citations · Full text

Drug Target, Engineering, Molecular Biology +21

Discovery of Pyrazolo[3,4- <i>d</i> ]pyridazinone Derivatives as Selective DDR1 Inhibitors via Deep Learning Based Design, Synthesis, and Biological Evaluation

Xiaoqin Tan, Chunpu Li, Ruirui Yang et al. · Journal of Medicinal Chemistry · 2021 · 63 citations · Full text

Drug repurposing against breast cancer by integrating drug-exposure expression profiles and drug–drug links based on graph neural network

Chen Cui, Xiaoyu Ding, Dingyan Wang et al. · Bioinformatics · 2021 · 48 citations · Full text

A hybrid framework for improving uncertainty quantification in deep learning-based QSAR regression modeling

Dingyan Wang, Jie Yu, Lifan Chen et al. · Journal of Cheminformatics · 2021 · 43 citations · Full text