Chunpu Li

Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease

Wenhao Dai, Bing Zhang, Xia-Ming Jiang et al. · Science · 2020 · 1.6K citations · Full text

Tanshinone IIA inhibits β-catenin/VEGF-mediated angiogenesis by targeting TGF-β1 in normoxic and HIF-1α in hypoxic microenvironments in human colorectal cancer

Hua Sui, Jihui Zhao, Lihong Zhou et al. · Cancer Letters · 2017 · 159 citations

Angiogenesis, Oncology, Chemoprevention Strategy +12

Deep Learning Enhancing Kinome-Wide Polypharmacology Profiling: Model Construction and Experiment Validation

Xutong Li, Zhaojun Li, Xiaolong Wu et al. · Journal of Medicinal Chemistry · 2019 · 102 citations

Discovery of Novel Janus Kinase (JAK) and Histone Deacetylase (HDAC) Dual Inhibitors for the Treatment of Hematological Malignancies

Xuewu Liang, Jie Zang, Xiaoyang Li et al. · Journal of Medicinal Chemistry · 2019 · 81 citations · Full text

Inhibition of β-catenin/B cell lymphoma 9 protein−protein interaction using α-helix–mimicking sulfono-γ-AApeptide inhibitors

Peng Sang, Min Zhang, Yan Shi et al. · Proceedings of the National Academy of Sciences · 2019 · 79 citations · Full text

α-Helix–mimicking Sulfono-γ-aapeptide Inhibitors, Immunology, Molecular Biology +20