Efficacy and safety of combined use of aliskiren and valsartan in patients with hypertension: a randomised, double-blind trial

Suzanne Oparil, Steven A. Yarows, Samir Patel, +3

The Lancet

Combined UseHypertensionCardiovascular DiseaseMedicineAntihypertensive Therapy +6

Renin inhibition with aliskiren provides additive antihypertensive efficacy when used in combination with hydrochlorothiazide

Alberto S. Villamil, Steven G. Chrysant, David A. Calhoun, +4

Journal of Hypertension

Efficacy and Safety of LCZ696, a First-in-Class Angiotensin Receptor Neprilysin Inhibitor, in Asian Patients With Hypertension

Kazuomi Kario, Ningling Sun, Fu‐Tien Chiang, +7

Hypertension

Loss of SATB1 Induces p21-Dependent Cellular Senescence in Post-mitotic Dopaminergic Neurons

Benjamin Kolisnyk, Tae Wan Kim, Jia Cheng, +13

Cell stem cell

Cellular SenescenceNeuroscienceMolecular NeurobiologyPost-mitotic Dopaminergic NeuronsMedicine +2

A cluster of cooperating tumor-suppressor gene candidates in chromosomal deletions

Wen Xue, Thomas Kitzing, Stéphanie Roessler, +15

Proceedings of the National Academy of Sciences

GeneticsMolecular GeneticsEpigeneticsTumor BiologyCancer Genomes +16

Aliskiren and the calcium channel blocker amlodipine combination as an initial treatment strategy for hypertension control (ACCELERATE): a randomised, parallel-group trial

Morris J. Brown, Gordon T. McInnes, Cheraz Cherif Papst, +2

The Lancet

HypertensionParallel-group TrialCardiovascular DiseaseAntihypertensive AgentsMedicine +8

Selective death of autoreactive T cells in human diabetes by TNF or TNF receptor 2 agonism

Liqin Ban, Jack Zhang, Limei Wang, +3

Proceedings of the National Academy of Sciences

Normal T CellsT-regulatory CellImmunologyImmune RegulationCell Death +17

Design and Synthesis of Novel α₁_a Adrenoceptor-Selective Antagonists. 1. Structure−Activity Relationship in Dihydropyrimidinones

Dhanapalan Nagarathnam, Shou Wu Miao, Bharat Lagu, +24

Journal of Medicinal Chemistry

Organic ChemistryPharmacotherapyChemistryPharmaceutical ChemistryMolecular Pharmacology +14

Safety and efficacy of LCZ696, a first-in-class angiotensin receptor neprilysin inhibitor, in Japanese patients with hypertension and renal dysfunction

Sadayoshi Ito, Minoru Satoh, Yuko Tamaki, +5

Hypertension Research

Antihypertensive efficacy, safety, and tolerability of the oral direct renin inhibitor aliskiren in patients with hypertension: a pooled analysis

Christopher Bush, David R. Anderson, Jack Zhang, +2

Journal of the American Society of Hypertension

HypertensionCardiovascular DiseaseAntihypertensive AgentsMedicineAntihypertensive Therapy +7