Renin inhibition with aliskiren provides additive antihypertensive efficacy when used in combination with hydrochlorothiazide - Concepedia

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Renin inhibition with aliskiren provides additive antihypertensive efficacy when used in combination with hydrochlorothiazide

284

Citations

18

References

2006

Year

Alberto S. Villamil, Steven G. Chrysant, David A. Calhoun, Bonnie Schober, Huang Hsu, Linda Matrisciano-Dimichino, Jack Zhang

Journal of Hypertension

Abstract

Aliskiren monotherapy demonstrated significant BP lowering, and its effect was considerably greater when combined with HCTZ. Renin inhibition with aliskiren neutralized the compensatory rise in PRA induced by HCTZ.

References

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