Concepedia

Wendy Lee

WL

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Publications

17

Citations

1.1K

H-Index

13

Active since

2010

Affiliations

Shanghai Zhangjiang Laboratory(Current)

Automotive Fuel Cell Cooperation (Canada)

Simon Fraser University

Health and Functional Exposomics

Gene Therapy Laboratory

Wendy Lee is an author at Shanghai Zhangjiang Laboratory specializing in pharmacology, medicinal chemistry, and pharmacy.

ORCID

Publications per year

2010–2025

17

Publications

17

Discovery of GDC-0853: A Potent, Selective, and Noncovalent Bruton’s Tyrosine Kinase Inhibitor in Early Clinical Development

James J. Crawford, Adam R. Johnson, Dinah Misner et al. · Journal of Medicinal Chemistry · 2018 · 247 citations · Full text

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An allosteric pan-TEAD inhibitor blocks oncogenic YAP/TAZ signaling and overcomes KRAS G12C inhibitor resistance

Thijs J. Hagenbeek, Marc Hafner, Rana Mroue et al. · Nature Cancer · 2023 · 195 citations · Full text

, , +17

Small Molecule Dysregulation of TEAD Lipidation Induces a Dominant-Negative Inhibition of Hippo Pathway Signaling

Jeffrey K. Holden, James J. Crawford, Cameron L. Noland et al. · Cell Reports · 2020 · 173 citations · Full text

, , +13

Design of Selective PAK1 Inhibitor G-5555: Improving Properties by Employing an Unorthodox Low-p <i>K</i> <sub>a</sub> Polar Moiety

Chudi Ndubaku, James J. Crawford, Joy Drobnick et al. · ACS Medicinal Chemistry Letters · 2015 · 86 citations · Full text

, , +10

Chemically Diverse Group I p21-Activated Kinase (PAK) Inhibitors Impart Acute Cardiovascular Toxicity with a Narrow Therapeutic Window

Joachim Rudolph, Lesley Murray, Chudi Ndubaku et al. · Journal of Medicinal Chemistry · 2016 · 77 citations · Full text

, , +13

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