Simon Cocklin

Small-molecule inhibitors of HIV-1 entry block receptor-induced conformational changes in the viral envelope glycoproteins

Zhihai Si, Navid Madani, Jason M. Cox et al. · Proceedings of the National Academy of Sciences · 2004 · 255 citations

Life Sciences, Molecular Biology, Pharmacology +17

Inhibition of Homologous Recombination in Human Cells by Targeting RAD51 Recombinase

Fei Huang, Olga M. Mazina, Isaac Zentner et al. · Journal of Medicinal Chemistry · 2012 · 150 citations · Full text

Medicine, Molecular Biology, Oncology +17

Design, synthesis and structure-activity relationships of 4-phenyl-1H-1,2,3-triazole phenylalanine derivatives as novel HIV-1 capsid inhibitors with promising antiviral activities

Lin Sun, Tianguang Huang, Alexej Dick et al. · European Journal of Medicinal Chemistry · 2020 · 111 citations · Full text

Pharmacy, Chemistry, Medicinal Chemistry +16

Targeting BRCA1- and BRCA2-deficient cells with RAD52 small molecule inhibitors

Fei Huang, Nadish Goyal, Katherine Sullivan et al. · Nucleic Acids Research · 2016 · 96 citations · Full text

Life Sciences, Molecular Biology, Oncology +13

High-resolution crystal structure reveals molecular details of target recognition by bacitracin

Nicoleta J. Economou, Simon Cocklin, Patrick J. Loll · Proceedings of the National Academy of Sciences · 2013 · 95 citations · Full text

Life Sciences, Biology, Microbiology +17