Inhibition of Homologous Recombination in Human Cells by Targeting RAD51 Recombinase

Fei Huang, Olga M. Mazina, Isaac Zentner, +2

Journal of Medicinal Chemistry

Gene TherapiesGenome InstabilityDna DamageHuman CellsHomologous Recombination +12

Inhibiting Early-Stage Events in HIV-1 Replication by Small-Molecule Targeting of the HIV-1 Capsid

Sandhya Kortagere, Navid Madani, Marie K. Mankowski, +18

Journal of Virology

Chimeric antigen receptor macrophages (CAR-M) sensitize HER2+ solid tumors to PD1 blockade in pre-clinical models

Stefano Pierini, Rashid Gabbasov, Maria Cecília Oliveira-Nunes, +27

Nature Communications

Tumor ImmunologyCancer ImmunosurveillanceImmunologyImmune Checkpoint InhibitorPre-clinical Models +6

IgG Binding Characteristics of Rhesus Macaque FcγR

Ying N. Chan, Austin W. Boesch, Nana Yaw Osei‐Owusu, +13

The Journal of Immunology

Structural Determinants for Affinity Enhancement of a Dual Antagonist Peptide Entry Inhibitor of Human Immunodeficiency Virus Type-1

Hosahudya N. Gopi, M. Umashankara, Vanessa Pirrone, +15

Journal of Medicinal Chemistry

Introducing metallocene into a triazole peptide conjugate reduces its off‐rate and enhances its affinity and antiviral potency for HIV‐1 gp120

Hosahudya N. Gopi, Simon Cocklin, Vanessa Pirrone, +8

Journal of Molecular Recognition

Identification of a Small‐Molecule Inhibitor of HIV‐1 Assembly that Targets the Phosphatidylinositol (4,5)‐bisphosphate Binding Site of the HIV‐1 Matrix Protein

Isaac Zentner, Luz‐Jeannette Sierra, Ayesha K. Fraser, +6

ChemMedChem

The Active Core in a Triazole Peptide Dual‐Site Antagonist of HIV‐1 gp120

Muddegowda Umashankara, Karyn McFadden, Isaac Zentner, +8

ChemMedChem

A Carrier Protein Strategy Yields the Structure of Dalbavancin

Nicoleta J. Economou, Virginie Nahoum, S.D. Weeks, +6

Journal of the American Chemical Society

Carrier Protein StrategyDrug TargetBiochemistryNatural SciencesRational Drug Design +10

An Optimized, Synthetic DNA Vaccine Encoding the Toxin A and Toxin B Receptor Binding Domains of Clostridium difficile Induces Protective Antibody Responses<i>In Vivo</i>

Scott M. Baliban, Amanda Michael, Berje Shammassian, +13

Infection and Immunity