Sharon Lim

Targeting of the MNK–eIF4E axis in blast crisis chronic myeloid leukemia inhibits leukemia stem cell function

Sharon Lim, Tzuen Yih Saw, Min Zhang et al. · Proceedings of the National Academy of Sciences · 2013 · 142 citations · Full text

Medicine, Cell Biology, Oncology +17

Obesity-Associated <i>GNAS</i> Mutations and the Melanocortin Pathway

Edson Mendes de Oliveira, Julia M. Keogh, Fleur Talbot et al. · New England Journal of Medicine · 2021 · 95 citations · Full text

Medicine, Genetics, Molecular Genetics +16

Phosphorylation of the survival kinase Akt by superoxide is dependent on an ascorbate-reversible oxidation of PTEN

Sharon Lim, Marie‐Véronique Clement · Free Radical Biology and Medicine · 2007 · 55 citations

Life Sciences, Biochemistry, Molecular Biology +14

Optimization of Selective Mitogen-Activated Protein Kinase Interacting Kinases 1 and 2 Inhibitors for the Treatment of Blast Crisis Leukemia

Haiyan Yang, Lohitha Rao Chennamaneni, Melvyn Wai Tuck Ho et al. · Journal of Medicinal Chemistry · 2018 · 54 citations · Full text

Medicine, Oncology, Pharmacology +17

An Essential Role of the Cysteine-rich Domain of FZD4 in Norrin/Wnt Signaling and Familial Exudative Vitreoretinopathy

Kang Zhang, Yuko Harada, Xinran Wei et al. · Journal of Biological Chemistry · 2010 · 42 citations · Full text

Life Sciences, Genetics, Ophthalmology +15