Midbrain-like Organoids from Human Pluripotent Stem Cells Contain Functional Dopaminergic and Neuromelanin-Producing Neurons

Junghyun Jo, Yixin Xiao, Alfred Xuyang Sun, +20

Cell stem cell

Regenerative MedicineInduced Pluripotent Stem CellMedicineAdult Stem CellNeuromelanin-producing Neurons +11

Targeting of the MNK–eIF4E axis in blast crisis chronic myeloid leukemia inhibits leukemia stem cell function

Sharon Lim, Tzuen Yih Saw, Min Zhang, +10

Proceedings of the National Academy of Sciences

Lewy Body–like Inclusions in Human Midbrain Organoids Carrying Glucocerebrosidase and α‐Synuclein Mutations

Junghyun Jo, Lin Yang, Hoang‐Dai Tran, +17

Annals of Neurology

A Src Homology 3-binding Sequence on the C Terminus of Sprouty2 Is Necessary for Inhibition of the Ras/ERK Pathway Downstream of Fibroblast Growth Factor Receptor Stimulation

Dieu-Hung Lao, Sumana Chandramouli, Permeen Yusoff, +6

Journal of Biological Chemistry

Cell GrowthTumor BiologyRas/erk Pathway DownstreamCell RegulationSignaling Pathway +16

Comparison of different test models for the assessment of cytotoxicity of composite resins

Tong Cao, Tzuen Yih Saw, Boon Chin Heng, +3

Journal of Applied Toxicology

Direct Binding of PP2A to Sprouty2 and Phosphorylation Changes Are a Prerequisite for ERK Inhibition Downstream of Fibroblast Growth Factor Receptor Stimulation

Dieu-Hung Lao, Permeen Yusoff, Sumana Chandramouli, +6

Journal of Biological Chemistry

Tooth slice organ culture and established cell line culture models for cytotoxicity assessment of dental materials

Tzuen Yih Saw, Tong Cao, Adrian Ujin Yap, +1

Toxicology in Vitro

Tissue EngineeringDental MaterialsEngineeringMedicineOral Cavity +9

Comparative hepatoprotective effects of tocotrienol analogs against drug-induced liver injury

Cheau Yih Tan, Tzuen Yih Saw, Chee Wai Fong, +1

Redox Biology

Tocotrienol AnalogsSpecific AnalogsLipid PeroxidationToxicological MechanismOxidative Stress +16

Composite cure and pulp-cell cytotoxicity associated with LED curing lights.

Adrian Ujin Yap, Tzuen Yih Saw, Tong Cao, +1

PubMed

Light RegulationPulp-cell CytotoxicityEngineeringOphthalmologyDental Biomechanics +7

Oral Supplementation of Tocotrienol-Rich Fraction Alleviates Severity of Ulcerative Colitis in Mice

Tzuen Yih Saw, Najib Abdul MALIK, Kee Pah Lim, +6

Journal of Nutritional Science and Vitaminology

NutritionGastrointestinal PharmacologyImmunologyGastroenterologyOxidative Stress +15