David S. Grierson

The purines: Potent and versatile small molecule inhibitors and modulators of key biological targets

Michel Legraverend, David S. Grierson · Bioorganic & Medicinal Chemistry · 2006 · 326 citations

Medicine, Medicinal Chemistry, Pharmacology +14

Chiral 1,4-dihydropyridine equivalents: a new approach to the asymmetric synthesis of alkaloids. The enantiospecific synthesis of (+)- and (-)-coniine and dihydropinidine

Luc Guerrier, Jacques Royer, David S. Grierson et al. · Journal of the American Chemical Society · 1983 · 215 citations

Natural Sciences, Chemistry, Medicinal Chemistry +7

Inhibition of nonsense-mediated mRNA decay (NMD) by a new chemical molecule reveals the dynamic of NMD factors in P-bodies

Sébastien Durand, Nicolas Cougot, Florence Mahuteau‐Betzer et al. · The Journal of Cell Biology · 2007 · 175 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15

Stereoselective Direct Copper-Catalyzed Alkenylation of Oxazoles with Bromoalkenes

François Besselièvre, Sandrine Piguel, Florence Mahuteau‐Betzer et al. · Organic Letters · 2008 · 143 citations

Natural Sciences, Chemistry, Medicinal Chemistry +10

Crystal Structures for HIV-1 Reverse Transcriptase in Complexes with Three Pyridinone Derivatives:  A New Class of Non-Nucleoside Inhibitors Effective against a Broad Range of Drug-Resistant Strains

D.M. Himmel, Kalyan Das, Arthur D. Clark et al. · Journal of Medicinal Chemistry · 2005 · 137 citations

Life Sciences, Medicinal Chemistry, Molecular Biology +17