LRRK2 regulates synaptogenesis and dopamine receptor activation through modulation of PKA activity

Loukia Parisiadou, Jia Yu, Carmelo Sgobio, +8

Nature Neuroscience

Signal TransductionMolecular PhysiologyMolecular NeuroscienceSignaling PathwayReceptor Tyrosine Kinase +11

Aldehyde dehydrogenase 1 defines and protects a nigrostriatal dopaminergic neuron subpopulation

Guoxiang Liu, Jia Yu, Jinhui Ding, +9

Journal of Clinical Investigation

Loss of NAD-Dependent Protein Deacetylase Sirtuin-2 Alters Mitochondrial Protein Acetylation and Dysregulates Mitophagy

Guoxiang Liu, Seong‐Hoon Park, Marta Imbesi, +6

Antioxidants and Redox Signaling

SIRT2-Mediated Deacetylation and Tetramerization of Pyruvate Kinase Directs Glycolysis and Tumor Growth

Seong‐Hoon Park, Özkan Özden, Guoxiang Liu, +11

Cancer Research

Metabolic RemodelingCancer BiologyTumor BiologyPkm2 RegulationCell Regulation +20

EMT and Acquisition of Stem Cell-Like Properties Are Involved in Spontaneous Formation of Tumorigenic Hybrids between Lung Cancer and Bone Marrow-Derived Mesenchymal Stem Cells

Meihua Xu, Xuan Gao, Dan Luo, +3

PLoS ONE

Adult Stem CellCell FusionStem Cell BiologyCancer BiologyTumor Biology +16

Mutations in GBA2 Cause Autosomal-Recessive Cerebellar Ataxia with Spasticity

Monia Hammer, Ghada Eleuch-Fayache, Lucía Schottlaender, +16

The American Journal of Human Genetics

Mendelian DisorderGenetic DisorderDegenerative DiseaseNeuroscienceNeurology +2

Selective expression of Parkinson's disease-related<i>Leucine-rich repeat kinase 2</i>G2019S missense mutation in midbrain dopaminergic neurons impairs dopamine release and dopaminergic gene expression

Guoxiang Liu, Carmelo Sgobio, Xinglong Gu, +12

Human Molecular Genetics

Synaptic SignalingSocial SciencesSelective ExpressionDopamine SynthesisNeurobiology Of Disease +16

A Combined Transcriptomic and Proteomic Approach to Reveal the Effect of Mogroside V on OVA-Induced Pulmonary Inflammation in Mice

Tong Dou, Juan Wang, Yisa Liu, +8

Frontiers in Immunology

Mogroside V reduce OVA-induced pulmonary inflammation based on lung and serum metabolomics

Yisa Liu, Juan Wang, Xiao Guan, +11

Phytomedicine

InflammationAsthmaInflammatory Lung DiseaseOva-induced Pulmonary InflammationLung Inflammation +10

Mesenchymal stem cells promote cell invasion and migration and autophagy‐induced epithelial‐mesenchymal transition in A549 lung adenocarcinoma cells

Dan Luo, Shiyuan Hu, Chunlan Tang, +1

Cell Biochemistry and Function