Enriched environment promotes behavioral and morphological recovery in a mouse model for the fragile X syndrome

Leonardo Restivo, Francesca Ferrari, Enrica Passino, +5

Proceedings of the National Academy of Sciences

NeuropsychologyGeneticsSocial SciencesHereditary Mental RetardationMorphological Recovery +17

LRRK2 regulates synaptogenesis and dopamine receptor activation through modulation of PKA activity

Loukia Parisiadou, Jia Yu, Carmelo Sgobio, +8

Nature Neuroscience

Signal TransductionMolecular PhysiologyMolecular NeuroscienceSignaling PathwayReceptor Tyrosine Kinase +11

Conditional Expression of Parkinson's Disease-Related Mutant  -Synuclein in the Midbrain Dopaminergic Neurons Causes Progressive Neurodegeneration and Degradation of Transcription Factor Nuclear Receptor Related 1

Xian Lin, Loukia Parisiadou, Carmelo Sgobio, +14

Journal of Neuroscience

Distinct Levels of Dopamine Denervation Differentially Alter Striatal Synaptic Plasticity and NMDA Receptor Subunit Composition

Vincent Paillé, Barbara Picconi, Vincenza Bagetta, +11

Journal of Neuroscience

Synaptic TransmissionNeurotransmitterDistinct LevelsNeurotransmissionStructural Plasticity +15

Synaptic vesicle glycoprotein 2C (SV2C) modulates dopamine release and is disrupted in Parkinson disease

Amy R. Dunn, Kristen A. Stout, Minagi Ozawa, +10

Proceedings of the National Academy of Sciences

Synaptic TransmissionNeurotransmitterNeurochemical BiomarkersClinical NeuroscienceNeurotransmission +20

Mechanisms underlying the impairment of hippocampal long-term potentiation and memory in experimental Parkinson’s disease

Cinzia Costa, Carmelo Sgobio, Sabrina Siliquini, +16

Brain

Inhibition of phosphodiesterases rescues striatal long-term depression and reduces levodopa-induced dyskinesia

Barbara Picconi, Vincenza Bagetta, Veronica Ghiglieri, +8

Brain

Dopamine-Dependent Long-Term Depression Is Expressed in Striatal Spiny Neurons of Both Direct and Indirect Pathways: Implications for Parkinson's Disease

Vincenza Bagetta, Barbara Picconi, S Marinucci, +5

Journal of Neuroscience

Plastic and behavioral abnormalities in experimental Huntington's disease: A crucial role for cholinergic interneurons

Barbara Picconi, Enrica Passino, Carmelo Sgobio, +7

Neurobiology of Disease

Neurobiological MechanismCholinergic InterneuronsNeuroanatomyMedicineRehabilitation +7

Hippocampal Synaptic Plasticity, Memory, and Epilepsy: Effects of Long-Term Valproic Acid Treatment

Carmelo Sgobio, Veronica Ghiglieri, Cinzia Costa, +9

Biological Psychiatry

Synaptic PlasticityNeuropsychologyPsychiatryNeurophysiologyMedicine +12