Kai Lü

Protease inhibitors targeting coronavirus and filovirus entry

Yanchen Zhou, P. Vedantham, Kai Lü et al. · Antiviral Research · 2015 · 616 citations · Full text

Protease Inhibitors, Antiviral Drug Development, Antiviral Therapy +4

Myocardial reparative functions of exosomes from mesenchymal stem cells are enhanced by hypoxia treatment of the cells via transferring microRNA-210 in an nSMase2-dependent way

Jinyun Zhu, Kai Lü, Ning Zhang et al. · Artificial Cells Nanomedicine and Biotechnology · 2017 · 258 citations · Full text

A Single Asparagine-Linked Glycosylation Site of the Severe Acute Respiratory Syndrome Coronavirus Spike Glycoprotein Facilitates Inhibition by Mannose-Binding Lectin through Multiple Mechanisms

Yanchen Zhou, Kai Lü, Susanne Pfefferle et al. · Journal of Virology · 2010 · 172 citations · Full text

Complement System, Multiple Mechanisms, Pathogenesis +12

IL-6 and PD-L1 blockade combination inhibits hepatocellular carcinoma cancer development in mouse model

Hu Liu, Jun Shen, Kai Lü · Biochemical and Biophysical Research Communications · 2017 · 147 citations

Pd-l1 Blockade Combination, Cancer Immunosurveillance, Immunology +7

Different host cell proteases activate the SARS-coronavirus spike-protein for cell–cell and virus–cell fusion

Graham Simmons, Stephanie Bertram, Ilona Glowacka et al. · Virology · 2011 · 130 citations

Viral Replication, Sars-coronavirus Spike-protein, Virus–cell Fusion +7