Yang Tang

Discovery of CRBN E3 Ligase Modulator CC-92480 for the Treatment of Relapsed and Refractory Multiple Myeloma

Joshua D. Hansen, Matthew Correa, Mark A. Nagy et al. · Journal of Medicinal Chemistry · 2020 · 218 citations · Full text

Medicine, Oncology, Pharmacology +13

Discovery of (<i>S</i>)-<i>N</i>-{2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methanesulfonylethyl]-1,3-dioxo-2,3-dihydro-1<i>H</i>-isoindol-4-yl}acetamide (Apremilast), a Potent and Orally Active Phosphodiesterase 4 and Tumor Necrosis Factor-α Inhibitor

Hon‐Wah Man, Peter Schäfer, Lu Min Wong et al. · Journal of Medicinal Chemistry · 2009 · 182 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

CC-90009: A Cereblon E3 Ligase Modulating Drug That Promotes Selective Degradation of GSPT1 for the Treatment of Acute Myeloid Leukemia

Joshua D. Hansen, Matthew Correa, Matt Alexander et al. · Journal of Medicinal Chemistry · 2021 · 149 citations · Full text

Medicine, Medicinal Chemistry, Oncology +13

Antioxidative effects of Panax notoginseng saponins in brain cells

Ningna Zhou, Yang Tang, Richard F. Keep et al. · Phytomedicine · 2014 · 100 citations · Full text

Life Sciences, Neuroscience, Pharmacology +16

Discovery and optimization of thieno[2,3-d]pyrimidines as B-Raf inhibitors

Garrick K. Packard, Patrick Papa, Jennifer R. Riggs et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 19 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12