Ryo Ito

Identification of Fused-Ring Alkanoic Acids with Improved Pharmacokinetic Profiles that Act as G Protein-Coupled Receptor 40/Free Fatty Acid Receptor 1 Agonists

Nobuyuki Negoro, Shinobu Sasaki, Masahiro Ito et al. · Journal of Medicinal Chemistry · 2012 · 64 citations · Full text

Peptide Science, Pharmacotherapy, Insulin Signaling +18

A Human Immortalized Cell-Based Blood–Brain Barrier Triculture Model: Development and Characterization as a Promising Tool for Drug−Brain Permeability Studies

Ryo Ito, Kenta Umehara, Shota Suzuki et al. · Molecular Pharmaceutics · 2019 · 58 citations

Discovery of Phenylpropanoic Acid Derivatives Containing Polar Functionalities as Potent and Orally Bioavailable G Protein-Coupled Receptor 40 Agonists for the Treatment of Type 2 Diabetes

Satoshi Mikami, Shuji Kitamura, Nobuyuki Negoro et al. · Journal of Medicinal Chemistry · 2012 · 52 citations · Full text

Pharmaceutical Science, Pharmacotherapy, Polar Substituents +18

Establishment and characterization of a new conditionally immortalized human astrocyte cell line

Tomomi Furihata, Ryo Ito, Atsuko Kamiichi et al. · Journal of Neurochemistry · 2015 · 48 citations · Full text

Hydrocortisone enhances the barrier properties of HBMEC/ciβ, a brain microvascular endothelial cell line, through mesenchymal-to-endothelial transition-like effects

Tomomi Furihata, Shinya Kawamatsu, Ryo Ito et al. · Fluids and Barriers of the CNS · 2015 · 40 citations · Full text