Concepedia

Shinobu Sasaki

SS

Statistics

Publications

19

Citations

755

H-Index

13

Active since

1989

Affiliations

Takeda (Japan)(Current)

Japan Atomic Energy Agency

Hitachi (Japan)

Hokkaido University

Shinobu Sasaki is an author at Takeda (Japan) specializing in pharmacology, drug discovery, and medicinal chemistry.

Publications per year

1989–2017

19

Publications

19

Discovery of TAK-875: A Potent, Selective, and Orally Bioavailable GPR40 Agonist

Nobuyuki Negoro, Shinobu Sasaki, Satoshi Mikami et al. · ACS Medicinal Chemistry Letters · 2010 · 247 citations · Full text

, , +17

Design, Synthesis, and Biological Activity of Potent and Orally Available G Protein-Coupled Receptor 40 Agonists

Shinobu Sasaki, Shuji Kitamura, Nobuyuki Negoro et al. · Journal of Medicinal Chemistry · 2011 · 87 citations · Full text

, , +17

Optimization of (2,3-Dihydro-1-benzofuran-3-yl)acetic Acids: Discovery of a Non-Free Fatty Acid-Like, Highly Bioavailable G Protein-Coupled Receptor 40/Free Fatty Acid Receptor 1 Agonist as a Glucose-Dependent Insulinotropic Agent

Nobuyuki Negoro, Shinobu Sasaki, Satoshi Mikami et al. · Journal of Medicinal Chemistry · 2012 · 73 citations · Full text

, , +15

Identification of Fused-Ring Alkanoic Acids with Improved Pharmacokinetic Profiles that Act as G Protein-Coupled Receptor 40/Free Fatty Acid Receptor 1 Agonists

Nobuyuki Negoro, Shinobu Sasaki, Masahiro Ito et al. · Journal of Medicinal Chemistry · 2012 · 64 citations · Full text

, , +7

Discovery of Phenylpropanoic Acid Derivatives Containing Polar Functionalities as Potent and Orally Bioavailable G Protein-Coupled Receptor 40 Agonists for the Treatment of Type 2 Diabetes

Satoshi Mikami, Shuji Kitamura, Nobuyuki Negoro et al. · Journal of Medicinal Chemistry · 2012 · 52 citations · Full text

, , +15

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