Yu Pang

Structure-Based Design of 6-Chloro-4-aminoquinazoline-2-carboxamide Derivatives as Potent and Selective p21-Activated Kinase 4 (PAK4) Inhibitors

Chenzhou Hao, Fan Zhao, Hongyan Song et al. · Journal of Medicinal Chemistry · 2017 · 64 citations · Full text

Combinatorial Chemistry, Drug Target, Pak4 Inhibitors +16

MORIN MITIGATES OXIDATIVE STRESS, APOPTOSIS AND INFLAMMATION IN CEREBRAL ISCHEMIC RATS

Yanrong Chen, Yanke Li, Huali Xu et al. · African Journal of Traditional Complementary and Alternative Medicines · 2017 · 59 citations · Full text

Design, synthesis, structure-activity relationships study and X-ray crystallography of 3-substituted-indolin-2-one-5-carboxamide derivatives as PAK4 inhibitors

Jing Guo, Fan Zhao, Wenbo Yin et al. · European Journal of Medicinal Chemistry · 2018 · 28 citations · Full text

Medicinal Chemistry, Structure-activity Relationships Study, Biochemistry +8

Discovery of 2-(4-Substituted-piperidin/piperazine-1-yl)-N-(5-cyclopropyl-1H-pyrazol-3-yl)-quinazoline-2,4-diamines as PAK4 Inhibitors with Potent A549 Cell Proliferation, Migration, and Invasion Inhibition Activity

Tianxiao Wu, Yu Pang, Jing Guo et al. · Molecules · 2018 · 17 citations · Full text

Synthesis, bioconversion, pharmacokinetic and pharmacodynamic evaluation of N-isopropyl-oxy-carbonyloxymethyl prodrugs of CZh-226, a potent and selective PAK4 inhibitor

Jing Guo, Tingting Wang, Tianxiao Wu et al. · European Journal of Medicinal Chemistry · 2019 · 15 citations · Full text

Pharmaceutical Science, Pharmaceutical Chemistry, Selective Pak4 Inhibitor +8