Matthias Brunner

Investigation of the interactions of critical scale-up parameters (pH, pO2 and pCO2) on CHO batch performance and critical quality attributes

Matthias Brunner, Jens Fricke, Paul Kröll et al. · Bioprocess and Biosystems Engineering · 2016 · 78 citations · Full text

Agriculture, Chemical Engineering, Food Science +16

Elevated pCO₂ affects the lactate metabolic shift in CHO cell culture processes

Matthias Brunner, Philipp Doppler, Tobias Klein et al. · Engineering in Life Sciences · 2017 · 62 citations · Full text

Life Sciences, Biochemistry, Cell Biology +16

The impact of pH inhomogeneities on CHO cell physiology and fed‐batch process performance – two‐compartment scale‐down modelling and intracellular pH excursion

Matthias Brunner, Philipp Braun, Philipp Doppler et al. · Biotechnology Journal · 2017 · 45 citations

Life Sciences, Cell Biology, Physiology +13

Quantification of cell lysis during CHO bioprocesses: Impact on cell count, growth kinetics and productivity

Tobias Klein, Nicole Heinzel, Paul Kröll et al. · Journal of Biotechnology · 2015 · 25 citations

Life Sciences, Biotechnology, Microbiology +17

Media photo‐degradation in pharmaceutical biotechnology – impact of ambient light on media quality, cell physiology, and IgG production in CHO cultures

Lukas Neutsch, Paul Kröll, Matthias Brunner et al. · Journal of Chemical Technology & Biotechnology · 2018 · 22 citations · Full text

Life Sciences, Biochemistry, Biotechnology +14