Hiroyuki Miyachi

(3-Substituted benzyl)thiazolidine-2,4-diones as structurally new antihyperglycemic agents

Masahiro Nomura, Susumu Kinoshita, Hiroya Satoh et al. · Bioorganic & Medicinal Chemistry Letters · 1999 · 105 citations · Full text

Medicinal Chemistry, Heterocyclic, Biochemistry +6

Design, Synthesis, and Evaluation of Substituted Phenylpropanoic Acid Derivatives as Human Peroxisome Proliferator Activated Receptor Activators. Discovery of Potent and Human Peroxisome Proliferator Activated Receptor α Subtype-Selective Activators

Masahiro Nomura, Takahiro Tanase, Tomohiro Ide et al. · Journal of Medicinal Chemistry · 2003 · 73 citations · Full text

Phenylpropanoic Acid Derivatives, Medicinal Chemistry, Pharmacological Study +11

Nuclear receptor antagonists designed based on the helix-folding inhibition hypothesis

Yuichi Hashimoto, Hiroyuki Miyachi · Bioorganic & Medicinal Chemistry · 2005 · 70 citations

Biochemistry, Functional Selectivity, Protein Folding +9

Tumor necrosis factor-alpha production-inhibiting activity of phthalimide analogues on human leukemia THP-1 cells and a structure-activity relationship study

Hiroyuki Miyachi, Asuka Ogasawara, Yuichi Hashimoto · Bioorganic & Medicinal Chemistry · 1997 · 60 citations

Factor-alpha Production-inhibiting Activity, Phthalimide Analogues, Medicine +9

Design, synthesis, and evaluation of cyclic amide/imide-bearing hydroxamic acid derivatives as class-selective histone deacetylase (HDAC) inhibitors

Chihiro Shinji, Satoko Maeda, Keisuke Imai et al. · Bioorganic & Medicinal Chemistry · 2006 · 54 citations

Medicinal Chemistry, Derivative (Chemistry), Biochemistry +10