Karsten Schmidt

Targeted delivery of antisense oligonucleotides to hepatocytes using triantennary<i>N</i>-acetyl galactosamine improves potency 10-fold in mice

Thazha P. Prakash, Mark J. Graham, Jinghua Yu et al. · Nucleic Acids Research · 2014 · 597 citations · Full text

Pharmacy, Molecular Pharmaceutics, Pharmacology +17

Contulakin-G, an O-Glycosylated Invertebrate Neurotensin

A. Grey Craig, Thomas Norberg, David C. Griffin et al. · Journal of Biological Chemistry · 1999 · 194 citations · Full text

Life Sciences, Biochemistry, Neuroscience +17

Comprehensive Structure–Activity Relationship of Triantennary<i>N</i>-Acetylgalactosamine Conjugated Antisense Oligonucleotides for Targeted Delivery to Hepatocytes

Thazha P. Prakash, Jinghua Yu, Michael T. Migawa et al. · Journal of Medicinal Chemistry · 2016 · 131 citations

Pharmacy, Pharmaceutics, Pharmacology +12

FoxL2 and Smad3 Coordinately Regulate Follistatin Gene Transcription

Amy L. Blount, Karsten Schmidt, Nicholas J. Justice et al. · Journal of Biological Chemistry · 2008 · 113 citations · Full text

Medicine, Endocrinology, Molecular Biology +11

Characterizing the effect of GalNAc and phosphorothioate backbone on binding of antisense oligonucleotides to the asialoglycoprotein receptor

Karsten Schmidt, Thazha P. Prakash, Aaron J. Donner et al. · Nucleic Acids Research · 2017 · 93 citations · Full text

Pharmacy, Molecular Biology, Pharmacology +17