Zhiqiang Zhao

Cyclic Hydroxyamidines as Amide Isosteres: Discovery of Oxadiazolines and Oxadiazines as Potent and Highly Efficacious γ-Secretase Modulators in Vivo

Z. J. Sun, Theodros Asberom, Thomas Bara et al. · Journal of Medicinal Chemistry · 2011 · 52 citations · Full text

Discovery of Novel Tricyclic Heterocycles as Potent and Selective DPP-4 Inhibitors for the Treatment of Type 2 Diabetes

Wen‐Lian Wu, Jinsong Hao, Martin S. Domalski et al. · ACS Medicinal Chemistry Letters · 2016 · 44 citations · Full text

Combinatorial Chemistry, Distinct Structures, X-ray Cocrystal Structures +17

Discovery of amide and heteroaryl isosteres as carbamate replacements in a series of orally active γ-secretase inhibitors

Mark D. McBriar, John W. Clader, Inhou Chu et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 42 citations · Full text

Medicinal Chemistry, Biochemistry, Medicine +9

2,6-Disubstituted N-arylsulfonyl piperidines as γ-secretase inhibitors

Dmitri Pissarnitski, Theodros Asberom, Thomas Bara et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 39 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Biochemistry +8

Tetrahydroquinoline sulfonamides as γ-secretase inhibitors

Theodros Asberom, Thomas Bara, John W. Clader et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 37 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Biochemistry +9