Aminopyridine-Based c-Jun N-Terminal Kinase Inhibitors with Cellular Activity and Minimal Cross-Kinase Activity

Bruce G. Szczepankiewicz, Christi Kosogof, Lissa T.J. Nelson, +23

Journal of Medicinal Chemistry

Little Inhibitory ActivityDrug TargetPharmacotherapyChemical BiologyDrug Resistance +19

Colorimetric detection of influenza A virus using antibody-functionalized gold nanoparticles

Yuanjian Liu, Linqun Zhang, Wei Wei, +4

The Analyst

Discovery of Potent, Selective, Orally Bioavailable Stearoyl-CoA Desaturase 1 Inhibitors

Gang Liu, J.A. Lynch, Jennifer C. Freeman, +17

Journal of Medicinal Chemistry

Metabolic SyndromeLong-chain Fatty AcidsBioavailable Scd1 InhibitorsPharmaceutical ScienceLipid Synthesis +12

Outcomes in Patients With Cardiac Amyloidosis Undergoing Heart Transplantation

Christopher D. Barrett, Kevin Alexander, Hongyu Zhao, +9

JACC Heart Failure

Heart FailureTransplantationCardiovascular DiseaseCardiac CareMedicine +2

Hydrogen sulfide improves colonic barrier integrity in DSS-induced inflammation in Caco-2 cells and mice

Hongyu Zhao, Rui Yan, Xiaogang Zhou, +2

International Immunopharmacology

InflammationMucosal ImmunologyColonic Barrier IntegrityMedicineHydrogen Sulfide +10

Integrating metabolomics and network pharmacology to explore the protective effect of gross saponins of Tribulus terrestris L. fruit against ischemic stroke in rat

Wenjun Guo, Yang Wang, Meiling Fan, +6

Journal of Ethnopharmacology

Network PharmacologyIschemic StrokeMedicineGross SaponinsPhysiology +10

Simultaneous fluorescent detection of multiplexed miRNA of liver cancer based on DNA tetrahedron nanotags

Hongyu Zhao, Minhui Wang, Xiaohui Xiong, +2

Talanta

NanomedicineEngineeringBiomedical DiagnosticsNanobiotechnologyBiomedical Imaging +9

SAR of amino pyrrolidines as potent and novel protein-protein interaction inhibitors of the PRC2 complex through EED binding

Michael L. Curtin, Marina Pliushchev, Huan‐Qiu Li, +18

Bioorganic & Medicinal Chemistry Letters

BiochemistryEed BindingMedicineNatural SciencesPrc2 Complex +9

Investigating the Protective Effect of Gross Saponins of Tribulus terrestris Fruit against Ischemic Stroke in Rat Using Metabolomics and Network Pharmacology

Yang Wang, Wenjun Guo, Yue Liu, +5

Metabolites

De Novo Design, Synthesis, and Biological Evaluation of 3,4-Disubstituted Pyrrolidine Sulfonamides as Potent and Selective Glycine Transporter 1 Competitive Inhibitors

Ying Wang, Hongyu Zhao, J.T. Brewer, +15

Journal of Medicinal Chemistry

3,4-Disubstituted Pyrrolidine SulfonamidesPharmacotherapyChemical BiologyPharmaceutical ChemistryMedicinal Chemistry +14