Bruce G. Szczepankiewicz

Discovery of a Potent, Selective Protein Tyrosine Phosphatase 1B Inhibitor Using a Linked-Fragment Strategy

Bruce G. Szczepankiewicz, Gang Liu, Philip J. Hajduk et al. · Journal of the American Chemical Society · 2003 · 228 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

SIRT1 Activation by Small Molecules

Han Dai, Lauren Kustigian, David P. Carney et al. · Journal of Biological Chemistry · 2010 · 213 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +10

Crystallographic structure of a small molecule SIRT1 activator-enzyme complex

Han Dai, April Case, Thomas V. Riera et al. · Nature Communications · 2015 · 203 citations · Full text

Life Sciences, Medicinal Chemistry, Molecular Biology +17

Aminopyridine-Based c-Jun N-Terminal Kinase Inhibitors with Cellular Activity and Minimal Cross-Kinase Activity

Bruce G. Szczepankiewicz, Christi Kosogof, Lissa T.J. Nelson et al. · Journal of Medicinal Chemistry · 2006 · 160 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Selective Protein Tyrosine Phosphatase 1B Inhibitors:  Targeting the Second Phosphotyrosine Binding Site with Non-Carboxylic Acid-Containing Ligands

Gang Liu, Zhili Xin, Heng Liang et al. · Journal of Medicinal Chemistry · 2003 · 106 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17