Oxygen and Air Nanobubble Water Solution Promote the Growth of Plants, Fishes, and Mice

Kosuke Ebina, Kenrin Shi, Makoto Hirao, +6

PLoS ONE

Total WeightEngineeringNanotoxicologyBrassica CampestrisGreen Nanotechnology +16

IL-6 negatively regulates osteoblast differentiation through the SHP2/MEK2 and SHP2/Akt2 pathways in vitro

Shoichi Kaneshiro, Kosuke Ebina, Kenrin Shi, +7

Journal of Bone and Mineral Metabolism

InflammationOsteoblast DifferentiationShp2/akt2 PathwaysBone Morphogenic ProteinImmunology +4

First-in-Human Pilot Study of Implantation of a Scaffold-Free Tissue-Engineered Construct Generated From Autologous Synovial Mesenchymal Stem Cells for Repair of Knee Chondral Lesions

Kazunori Shimomura, Yukihiko Yasui, Kota Koizumi, +12

The American Journal of Sports Medicine

Next Generation Mesenchymal Stem Cell (MSC)–Based Cartilage Repair Using Scaffold-Free Tissue Engineered Constructs Generated with Synovial Mesenchymal Stem Cells

Kazunori Shimomura, Wataru Ando, Yu Moriguchi, +7

Cartilage

Progranulin plays crucial roles in preserving bone mass by inhibiting TNF-α-induced osteoclastogenesis and promoting osteoblastic differentiation in mice

Takaaki Noguchi, Kosuke Ebina, Makoto Hirao, +9

Biochemical and Biophysical Research Communications

Developmental BiologyHealth SciencesOsteoarthritisBone MassSkeletal Biology +8

Vitamin K2 administration is associated with decreased disease activity in patients with rheumatoid arthritis

Kosuke Ebina, Kenrin Shi, Makoto Hirao, +5

Modern Rheumatology

Vitamin K2 administration is associated with decreased disease activity in patients with rheumatoid arthritis

Kosuke Ebina, Kenrin Shi, Makoto Hirao, +5

Modern Rheumatology

ImmunologyDecreased Disease ActivityPsoriatic ArthritisOsteoporosisInflammatory Arthritis +22

Preparation of Scaffold-Free Tissue-Engineered Constructs Derived from Human Synovial Mesenchymal Stem Cells Under Low Oxygen Tension Enhances Their Chondrogenic Differentiation Capacity

Yukihiko Yasui, Ryota Chijimatsu, David A. Hart, +6

Tissue Engineering Part A

Tissue EngineeringRegenerative MedicineEngineeringLow Oxygen TensionMedicine +12

Comparison of the effects of denosumab between a native vitamin D combination and an active vitamin D combination in patients with postmenopausal osteoporosis

Kosuke Ebina, Masafumi Kashii, Makoto Hirao, +8

Journal of Bone and Mineral Metabolism

Bone DiseaseBone HealthPostmenopausal OsteoporosisMenopauseBone Density +5

Stem Cell Therapy in Cartilage Repair—Culture-Free and Cell Culture–Based Methods

Norimasa Nakamura, James Hoi Po Hui, Kota Koizumi, +5

Operative Techniques in Orthopaedics

Tissue EngineeringCell TherapyEngineeringBiomedical EngineeringStem Cell Biology +15