Makoto Hirao

Oxygen and Air Nanobubble Water Solution Promote the Growth of Plants, Fishes, and Mice

Kosuke Ebina, Kenrin Shi, Makoto Hirao et al. · PLoS ONE · 2013 · 388 citations · Full text

Total Weight, Engineering, Nanotoxicology +18

IL-6 negatively regulates osteoblast differentiation through the SHP2/MEK2 and SHP2/Akt2 pathways in vitro

Shoichi Kaneshiro, Kosuke Ebina, Kenrin Shi et al. · Journal of Bone and Mineral Metabolism · 2013 · 208 citations

Inflammation, Osteoblast Differentiation, Shp2/akt2 Pathways +6

Oxygen Tension Regulates Chondrocyte Differentiation and Function during Endochondral Ossification

Makoto Hirao, Noriyuki Tamai, Noriyuki Tsumaki et al. · Journal of Biological Chemistry · 2006 · 190 citations · Full text

Oxidative Stress, Regenerative Medicine, Tissue Development +18

Identification of a novel arthritis-associated osteoclast precursor macrophage regulated by FoxM1

Tetsuo Hasegawa, Junichi Kikuta, Takao Sudo et al. · Nature Immunology · 2019 · 174 citations

Inflammation, Rheumatology, Autoimmune Disease +10

A new biotechnology for articular cartilage repair: subchondral implantation of a composite of interconnected porous hydroxyapatite, synthetic polymer (PLA-PEG), and bone morphogenetic protein-2 (rhBMP-2)

Noriyuki Tamai, Akira Myoui, Makoto Hirao et al. · Osteoarthritis and Cartilage · 2005 · 154 citations · Full text

Tissue Engineering, Regenerative Medicine, New Biotechnology +13