Dongming Liu

Evaluation of farnesyl:protein transferase and geranylgeranyl:protein transferase inhibitor combinations in preclinical models.

Robert B. Lobell, CharlesA. Omer, Marc Abrams et al. · PubMed · 2001 · 239 citations

Protein Transferase, H Infusion, Chemical Biology +18

Paired Design of dCas9 as a Systematic Platform for the Detection of Featured Nucleic Acid Sequences in Pathogenic Strains

Yihao Zhang, Long Qian, Weijia Wei et al. · ACS Synthetic Biology · 2016 · 181 citations

Systematic Platform, Paired Design, Pathogenic Strains +23

Preclinical and clinical pharmacodynamic assessment of L-778,123, a dual inhibitor of farnesyl:protein transferase and geranylgeranyl:protein transferase type-I.

Robert B. Lobell, Dongming Liu, Carolyn A. Buser et al. · PubMed · 2002 · 121 citations

Dual Inhibitor, Molecular Pharmacology, Pbmc Samples +15

LDLR inhibition promotes hepatocellular carcinoma proliferation and metastasis by elevating intracellular cholesterol synthesis through the MEK/ERK signaling pathway

Ziye Chen, Lu Chen, Bo Sun et al. · Molecular Metabolism · 2021 · 73 citations · Full text

PNO1 inhibits autophagy-mediated ferroptosis by GSH metabolic reprogramming in hepatocellular carcinoma

Xiaomeng Hu, Yuchao He, Zhiqiang Han et al. · Cell Death and Disease · 2022 · 73 citations · Full text