The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes

Tianpeng Gu, Fan Guo, Hui Yang, +14

Nature

ChromatinChromatin RemodelingNatural SciencesGeneticsMolecular Epigenetics +11

The DNA methylation landscape of human early embryos

Hongshan Guo, Ping Zhu, Liying Yan, +22

Nature

ChromatinDna Methylation LandscapeDevelopmental BiologyEpigenetic ChangeGenetics +6

The Transcriptome and DNA Methylome Landscapes of Human Primordial Germ Cells

Fan Guo, Liying Yan, Hongshan Guo, +25

Cell

ChromatinDevelopmental BiologyGerm Cell FateGerm CellEpigenetic Change +10

Single-Cell RNA-Seq Analysis Maps Development of Human Germline Cells and Gonadal Niche Interactions

Li Li, Ji Dong, Liying Yan, +21

Cell stem cell

Germ Cell BiologyDevelopmental BiologyGerm CellHuman Germline CellsMedicine +10

Off-target RNA mutation induced by DNA base editing and its elimination by mutagenesis

Changyang Zhou, Yidi Sun, Rui Yan, +11

Nature

Off-target Rna MutationGeneticsMolecular BiologyGenetic EngineeringGene Editing +5

Single-cell multi-omics sequencing of mouse early embryos and embryonic stem cells

Fan Guo, Lin Li, Jingyun Li, +5

Cell Research

Active and Passive Demethylation of Male and Female Pronuclear DNA in the Mammalian Zygote

Fan Guo, Xianlong Li, Dan Liang, +11

Cell stem cell

ChromatinNatural SciencesGeneticsMammalian ZygoteEpigenetic Change +11

Tet and TDG Mediate DNA Demethylation Essential for Mesenchymal-to-Epithelial Transition in Somatic Cell Reprogramming

Xiao Hu, Lei Zhang, Shi-Qing Mao, +8

Cell stem cell

ChromatinLineage PlasticityInduced Pluripotent Stem CellSomatic Cell GeneticsMedicine +10

Single-cell multi-omics sequencing of human early embryos

Lin Li, Fan Guo, Yun Gao, +11

Nature Cell Biology

Developmental BiologySingle Cell SequencingMedicineNeonatal Multi-omicsSingle-cell Genomics +8

Profiling DNA methylome landscapes of mammalian cells with single-cell reduced-representation bisulfite sequencing

Hongshan Guo, Ping Zhu, Fan Guo, +5

Nature Protocols

BioinformaticsChromatinFunctional GenomicsMammalian CellsMedicine +11