Wei Yan - Concepedia

Author

Wei Yan

Sichuan University ORCID

Also Known As

Wei Yan

Publications

520

Citations

H-Index

Concepts

All Affiliations

Sichuan University West China Hospital of Sichuan University State Key Laboratory of Biotherapy Chengdu University of Traditional Chinese Medicine

About

Wei Yan is an author at Sichuan University specializing in medicinal chemistry, drug discovery, and drug development.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	3	3	169
2	Engineering	1	1	34
3	Natural Sciences	1	1	32
4	Biochemistry	1	1	32
5	Biomolecular Engineering	1	1	27

Wei Yan

Publications

506

Citations

H-Index

Page 1

	Year	Citations
Design, Synthesis, and Evaluation of in Vitro and in Vivo Anticancer Activity of 4-Substituted Coumarins: A Novel Class of Potent Tubulin Polymerization Inhibitors Dong Cao, Yibin Liu, Wei Yan, Journal of Medicinal Chemistry Medicinal ChemistryVivo Anticancer ActivityPharmaceutical ChemistryPolymer-drug ConjugateMedicine	2016	110
Reversible binding of the anticancer drug KXO1 (tirbanibulin) to the colchicine-binding site of β-tubulin explains KXO1's low clinical toxicity Lu Niu, Jianhong Yang, Wei Yan, Journal of Biological Chemistry	2019	64
Cevipabulin-tubulin complex reveals a novel agent binding site on α-tubulin with tubulin degradation effect Jianhong Yang, Yamei Yu, Yong Li, Science Advances	2021	62
Covalent modification of Cys-239 in β-tubulin by small molecules as a strategy to promote tubulin heterodimer degradation Jianhong Yang, Yong Li, Wei Yan, Journal of Biological Chemistry	2019	46
Rapid and non-destructive measurement of biofuel pellet quality indices based on two-dimensional near infrared spectroscopic imaging Xuping Feng, Chenliang Yu, Zhenyu Shu, Fuel Infrared Spectroscopic ImagingEngineeringBioenergyBiorefinery ProductOptical Diagnostics	2018	34
Design, synthesis and biological evaluation of 4-anilinoquinoline derivatives as novel potent tubulin depolymerization agents Yuanyuan Zhou, Wei Yan, Dong Cao, European Journal of Medicinal Chemistry Combinatorial ChemistryMedicinal ChemistryPharmaceutical ScienceBiochemistryMedicine	2017	32
Design, Synthesis, and Bioactivity Evaluation of Dual-Target Inhibitors of Tubulin and Src Kinase Guided by Crystal Structure Lun Wang, Yunhua Zheng, Dan Li, Journal of Medicinal Chemistry	2021	28
Discovery of novel β-carboline/acylhydrazone hybrids as potent antitumor agents and overcome drug resistance Yong Li, Wei Yan, Jianhong Yang, European Journal of Medicinal Chemistry Medicinal ChemistryPotent Antitumor AgentsMedicineNovel β-Carboline/acylhydrazone HybridsPharmacological Agent	2018	27
The Natural Compound Withaferin A Covalently Binds to Cys239 of β-Tubulin to Promote Tubulin Degradation Jianhong Yang, Wei Yan, Yong Li, Molecular Pharmacology	2019	26
Structure-Based Design and Synthesis of N-Substituted 3-Amino-β-Carboline Derivatives as Potent αβ-Tubulin Degradation Agents Yong Li, Yan Liu, Zejiang Zhu, Journal of Medicinal Chemistry	2022	25

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