Wei Yan

Design, Synthesis, and Evaluation of in Vitro and in Vivo Anticancer Activity of 4-Substituted Coumarins: A Novel Class of Potent Tubulin Polymerization Inhibitors

Dong Cao, Yibin Liu, Wei Yan et al. · Journal of Medicinal Chemistry · 2016 · 111 citations

Medicine, Medicinal Chemistry, Pharmacology +15

Reversible binding of the anticancer drug KXO1 (tirbanibulin) to the colchicine-binding site of β-tubulin explains KXO1's low clinical toxicity

Lu Niu, Jianhong Yang, Wei Yan et al. · Journal of Biological Chemistry · 2019 · 68 citations · Full text

Medicine, Oncology, Pharmacology +17

Cevipabulin-tubulin complex reveals a novel agent binding site on α-tubulin with tubulin degradation effect

Jianhong Yang, Yamei Yu, Yong Li et al. · Science Advances · 2021 · 65 citations · Full text

Medicine, Oncology, Pharmacology +16

Covalent modification of Cys-239 in β-tubulin by small molecules as a strategy to promote tubulin heterodimer degradation

Jianhong Yang, Yong Li, Wei Yan et al. · Journal of Biological Chemistry · 2019 · 51 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

Rapid and non-destructive measurement of biofuel pellet quality indices based on two-dimensional near infrared spectroscopic imaging

Xuping Feng, Chenliang Yu, Zhenyu Shu et al. · Fuel · 2018 · 35 citations

Natural Sciences, Bioengineering, Chemistry +14