Design, synthesis and biological evaluation of a series of pyrano chalcone derivatives containing indole moiety as novel anti-tubulin agents

Guangcheng Wang, Chunyan Li, Lin He, +13

Bioorganic & Medicinal Chemistry

Pyrano Chalcone DerivativesBiochemistryMedicineIndole MoietyNovel Anti-tubulin Agents +4

Design, Synthesis, and Evaluation of in Vitro and in Vivo Anticancer Activity of 4-Substituted Coumarins: A Novel Class of Potent Tubulin Polymerization Inhibitors

Dong Cao, Yibin Liu, Wei Yan, +14

Journal of Medicinal Chemistry

Medicinal ChemistryVivo Anticancer ActivityPharmaceutical ChemistryPolymer-drug ConjugateMedicine +13

Discovery of Selective Histone Deacetylase 6 Inhibitors Using the Quinazoline as the Cap for the Treatment of Cancer

Zhuang Yang, Taijin Wang, Fang Wang, +12

Journal of Medicinal Chemistry

Selective Hdac6 InhibitorPharmaceutical ChemistryTumor BiologyHdac Enzymatic AssaysMolecular Pharmacology +14

Design, synthesis and biological evaluation of thiazole- and indole-based derivatives for the treatment of type II diabetes

Qinyuan Xu, Li Huang, Juan Liu, +14

European Journal of Medicinal Chemistry

Medicinal ChemistryBiochemistryNatural SciencesMedicinePharmacological Agent +7

Design, synthesis and biological evaluation of millepachine derivatives as a new class of tubulin polymerization inhibitors

Guangcheng Wang, Fei Peng, Dong Cao, +12

Bioorganic & Medicinal Chemistry

Bioorganic ChemistryMedicineDrug DiscoveryTubulin Polymerization InhibitorsNew Class +4

Synthesis and Biological Evaluation of Novel Millepachine Derivatives As a New Class of Tubulin Polymerization Inhibitors

Zhuang Yang, Wenshuang Wu, Jingjing Wang, +15

Journal of Medicinal Chemistry

Synthesis and biological evaluation of novel pyranochalcone derivatives as a new class of microtubule stabilizing agents

Dong Cao, Xiaolei Han, Guangcheng Wang, +17

European Journal of Medicinal Chemistry

Bioorganic ChemistryMedicineNovel Pyranochalcone DerivativesNew ClassBiological Evaluation +4

Design, synthesis, and structure–activity relationship studies of novel millepachine derivatives as potent antiproliferative agents

Guangcheng Wang, Wenshuang Wu, Fei Peng, +14

European Journal of Medicinal Chemistry

Potent Antiproliferative AgentsMedicinal ChemistryDerivative (Chemistry)Natural SciencesMedicine +7

Design, synthesis and biological evaluation of 4-anilinoquinoline derivatives as novel potent tubulin depolymerization agents

Yuanyuan Zhou, Wei Yan, Dong Cao, +9

European Journal of Medicinal Chemistry

Combinatorial ChemistryMedicinal ChemistryPharmaceutical ScienceBiochemistryMedicine +7

Rational design, synthesis, and pharmacological properties of pyranochalcone derivatives as potent anti-inflammatory agents

Fei Peng, Guangcheng Wang, Xiuxia Li, +14

European Journal of Medicinal Chemistry

Medicinal ChemistryAnti-inflammatoryBiochemistryRational DesignPyranochalcone Derivatives +6