Pyruvate carboxylase supports the pulmonary tropism of metastatic breast cancer

Aparna Shinde, Tomasz Wilmanski, Hao Chen, +2

Breast Cancer Research

Dimethyloxalylglycine Prevents Bone Loss in Ovariectomized C57BL/6J Mice through Enhanced Angiogenesis and Osteogenesis

Jia Peng, Zuo Gui Lai, Zhang Lian Fang, +9

PLoS ONE

Bone RepairOsteogenesisBone DevelopmentOsteoporosisOrthopaedic Surgery +21

Britanin Ameliorates Cerebral Ischemia–Reperfusion Injury by Inducing the Nrf2 Protective Pathway

Guozhen Wu, Xing Yuan, Hao Chen, +8

Antioxidants and Redox Signaling

Neuroprotective effects of resveratrol on ischemic injury mediated by modulating the release of neurotransmitter and neuromodulator in rats

Chao Li, Zhiying Yan, Jing Yang, +4

Neurochemistry International

MedicineLipid PeroxidationPharmacologyNeuropharmacologyBrain Injury +11

A small molecule inhibitor of PTP1B and PTPN2 enhances T cell anti-tumor immunity

Shuwei Liang, Eric Tran, Xin Du, +11

Nature Communications

ImmunologyImmunoeditingSmall Molecule InhibitorImmunotherapeuticsT Cells +16

SHP2 is a multifunctional therapeutic target in drug resistant metastatic breast cancer

Hao Chen, Sarah Libring, Kasi Viswanatharaju Ruddraraju, +4

Oncogene

Anterior gradient 2 is a binding stabilizer of hypoxia inducible factor‐1α that enhances CoCl₂‐induced doxorubicin resistance in breast cancer cells

Zheqi Li, Qi Zhu, Lingyun Hu, +3

Cancer Science

Tumor BiologyAnterior Gradient 2Hypoxia-induced Doxorubicin ResistanceDoxorubicin ResistanceBreast Oncology +12

Low bone turnover and reduced angiogenesis in streptozotocin-induced osteoporotic mice

Jia Peng, Hui Kang, Hao Chen, +11

Connective Tissue Research

SclerostinOsteogenesisOrthopaedic SurgeryOsteoporosisType 1 +17

Platelet membrane fusion liposome loaded with type I AIE photosensitizer to induce chemoresistance cancer pyroptosis and immunogenic cell death for enhancing cancer immunotherapy

Hao Chen, Xi Luo, Qinghua Huang, +5

Chemical Engineering Journal

Photodynamic TherapyMedicineImmunogenic Cell DeathImmunologyChemoresistance Cancer Pyroptosis +8

Ubiquitin C‐Terminal Hydrolase L1: Biochemical and Cellular Characterization of a Covalent Cyanopyrrolidine‐Based Inhibitor

Aaron D. Krabill, Hao Chen, Sajjad Hussain, +8

ChemBioChem

Cellular CharacterizationMolecular BiologyC-terminal Hydrolase L1Chemical BiologyCancer Biology +17