Britanin Ameliorates Cerebral Ischemia–Reperfusion Injury by Inducing the Nrf2 Protective Pathway

Guozhen Wu, Xing Yuan, Hao Chen, +8

Antioxidants and Redox Signaling

Total sesquiterpene lactones prepared from Inula helenium L. has potentials in prevention and therapy of rheumatoid arthritis

Shuang Gao, Qun Wang, Xin-Hui Tian, +6

Journal of Ethnopharmacology

RheumatologyAnti-inflammatoryAllergyTotal Sesquiterpene LactonesMedicine +6

Discovery of Potent Small-Molecule Inhibitors of Ubiquitin-Conjugating Enzyme UbcH5c from α-Santonin Derivatives

Hao Chen, Guozhen Wu, Shuang Gao, +14

Journal of Medicinal Chemistry

Positive Compound 1Drug TargetChemoprevention StrategyImmunologyPeptide Science +24

Delavatine A, an unusual isoquinoline alkaloid exerts anti-inflammation on LPS-induced proinflammatory cytokines production by suppressing NF-κB activation in BV-2 microglia

Qing Xie, Guozhen Wu, Niao Yang, +3

Biochemical and Biophysical Research Communications

InflammationAnti-inflammatoryBv-2 MicrogliaMedicineImmune Regulation +10

Stereoselective and site-divergent synthesis of C-glycosides

Sheng Xu, Yuanyuan Ping, Minghao Xu, +5

Nature Chemistry

Site-divergent SynthesisGlycobiologyStereoselective SynthesisBiomolecular EngineeringGlycosylation

Bruceine D inhibits hepatocellular carcinoma growth by targeting β-catenin/jagged1 pathways

Ziying Cheng, Yuan Xing, Yi Qu, +13

Cancer Letters

Tumor BiologyMedicineLiver PhysiologyPathologyCancer Cell Biology +6

Chlorajaponols A–F, sesquiterpenoids from Chloranthus japonicus and their in vitro anti-inflammatory and anti-tumor activities

Zhi‐Guo Zhuo, Guozhen Wu, Xin Fang, +7

Fitoterapia

BiochemistryAnti-tumor ActivitiesChloranthus JaponicusChlorajaponols A–fPhytochemical +3

Total sesquiterpene lactones isolated from Inula helenium L . attenuates 2,4-dinitrochlorobenzene-induced atopic dermatitis-like skin lesions in mice

Qun Wang, Shuang Gao, Guozhen Wu, +8

Phytomedicine

Inula Helenium LMedicinal ChemistryAtopic DermatitisTotal Sesquiterpene LactonesDermatitis-like Skin Lesions +7

Astragaloside IV Attenuates Glutamate-Induced Neurotoxicity in PC12 Cells through Raf-MEK-ERK Pathway

Rongcai Yue, Xia Li, Bingyang Chen, +9

PLoS ONE

Comparative ProteomicsNeurotransmitterImmunologyCell DeathOxidative Stress +19

Vlasouliolides A-D, four rare C17/C15 sesquiterpene lactone dimers with potential anti-inflammatory activity from Vladimiria souliei

Liping Chen, Guozhen Wu, Jianping Zhang, +5

Scientific Reports