Lactate Is a Natural Suppressor of RLR Signaling by Targeting MAVS

Weina Zhang, Guihua Wang, Zhigang Xu, +23

Cell

Signal TransductionSignaling PathwayCell RegulationImmunologyRlr Signaling +7

An active contour model based on local fitted images for image segmentation

Lei Wang, Yan Chang, Hui Wang, +2

Information Sciences

Geometric ModelingMachine VisionImage AnalysisMedical ImagingEngineering +10

Active contours driven by edge entropy fitting energy for image segmentation

Lei Wang, Guangqiang Chen, Dai Shi, +4

Signal Processing

Geometric ModelingMachine VisionImage AnalysisMedical ImagingActive Contours +12

Radiomics analysis for the differentiation of autoimmune pancreatitis and pancreatic ductal adenocarcinoma in ¹⁸F‐FDG PET/CT

Yuquan Zhang, Chao Cheng, Zhaobang Liu, +6

Medical Physics

Cdk1-phosphorylated CUEDC2 promotes spindle checkpoint inactivation and chromosomal instability

Yanfei Gao, Teng Li, Yan Chang, +19

Nature Cell Biology

Genome InstabilityCell RegulationCell DivisionCell DeathCell Cycle +4

PERK activation by CCT020312 chemosensitizes colorectal cancer through inducing apoptosis regulated by ER stress

Yunpeng Lei, Lirui He, Yan Chang, +2

Biochemical and Biophysical Research Communications

MedicineApoptosisPerk ActivationColorectal CancerPathology +6

Differentiated cancer cell-originated lactate promotes the self-renewal of cancer stem cells in patient-derived colorectal cancer organoids

Hui Zhao, Yan Chang, Yibing Hu, +7

Cancer Letters

Lineage PlasticityMedicineCancer Cell-originated LactateColorectal CancerStem Cell Research +8

Ubiquitin-associated Domain-containing Ubiquitin Regulatory X (UBX) Protein UBXN1 Is a Negative Regulator of Nuclear Factor κB (NF-κB) Signaling

Yübo Wang, Bo Tan, Rui Mu, +11

Journal of Biological Chemistry

Targeting Orai1-mediated store-operated calcium entry by RP4010 for anti-tumor activity in esophagus squamous cell carcinoma

Chaochu Cui, Yan Chang, Xiaoli Zhang, +6

Cancer Letters

Esophageal CancerMedicinePharmacologyTumor TargetingAnti-cancer Agent +6

Sphere‑forming assay vs. organoid culture: Determining long‑term stemness and the chemoresistant capacity of primary colorectal cancer cells

Hui Zhao, Yan Chang, Yibing Hu, +6

International Journal of Oncology

PathologyCell CultureStem Cell BiologyTumor BiologyTumor Heterogeneity +16