Lactate Is a Natural Suppressor of RLR Signaling by Targeting MAVS

Identification and Characterization of MAVS, a Mitochondrial Antiviral Signaling Protein that Activates NF-κB and IRF3

Rashu B. Seth, Lijun Sun, Chee-Kwee Ea et al. · Cell · 2005 · 3.3K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +10

Functional polarization of tumour-associated macrophages by tumour-derived lactic acid

Oscar R. Colegio, Ngoc-Quynh Chu, Alison L. Szabo et al. · Nature · 2014 · 2.9K citations

Life Sciences, Cell Biology, Immunology +16

A diverse range of gene products are effectors of the type I interferon antiviral response

John W. Schoggins, Sam J. Wilson, Maryline Panis et al. · Nature · 2011 · 2.5K citations

Life Sciences, Immunology, Molecular Biology +16

Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis

Chih‐Hao Chang, Jonathan D. Curtis, Leonard B. Maggi et al. · Cell · 2013 · 2.2K citations · Full text

Life Sciences, Biochemistry, Cell Biology +16

LDHA-Associated Lactic Acid Production Blunts Tumor Immunosurveillance by T and NK Cells

Almut Brand, Katrin Singer, Gudrun E. Koehl et al. · Cell Metabolism · 2016 · 1.9K citations · Full text

Life Sciences, Immunology, Oncology +12