You Chen

H3K9 methylation is a barrier during somatic cell reprogramming into iPSCs

Jiekai Chen, Liu He, Jing Liu et al. · Nature Genetics · 2012 · 490 citations

Life Sciences, Cell Biology, Molecular Biology +13

BMPs functionally replace Klf4 and support efficient reprogramming of mouse fibroblasts by Oct4 alone

Jiekai Chen, Jing Liu, Jiaqi Yang et al. · Cell Research · 2010 · 154 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +8

Intronic pentanucleotide TTTCA repeat insertion in the SAMD12 gene causes familial cortical myoclonic tremor with epilepsy type 1

Zhidong Cen, Zhengwen Jiang, You Chen et al. · Brain · 2018 · 100 citations

Life Sciences, Genetics, Molecular Genetics +17

Rational optimization of reprogramming culture conditions for the generation of induced pluripotent stem cells with ultra-high efficiency and fast kinetics

Jiekai Chen, Jing Liu, You Chen et al. · Cell Research · 2011 · 96 citations

Life Sciences, Bioengineering, Biotechnology +14

Biallelic loss-of-function mutations in JAM2 cause primary familial brain calcification

Zhidong Cen, You Chen, Si Chen et al. · Brain · 2019 · 93 citations · Full text

Life Sciences, Genetics, Molecular Genetics +15