H3K9 methylation is a barrier during somatic cell reprogramming into iPSCs

Jiekai Chen, Liu He, Jing Liu, +17

Nature Genetics

ChromatinSomatic Cell GeneticsNatural SciencesEpigenetic ChangeDna Methylation +9

Vitamin C modulates TET1 function during somatic cell reprogramming

Jiekai Chen, Lin Guo, Lei Zhang, +19

Nature Genetics

Cell RegulationSomatic Cell GeneticsVitamin CMedicineCell Biology +3

Sequential introduction of reprogramming factors reveals a time-sensitive requirement for individual factors and a sequential EMT–MET mechanism for optimal reprogramming

Xiaopeng Liu, Hao Sun, Jing Qi, +12

Nature Cell Biology

Sequential Emt–met MechanismEngineeringComputer EngineeringComputer ArchitectureSystems Engineering +3

Transient Activation of Autophagy via Sox2-Mediated Suppression of mTOR Is an Important Early Step in Reprogramming to Pluripotency

Shuo Wang, Pengyan Xia, Buqing Ye, +3

Cell stem cell

Cell AutophagyMitophagySignal TransductionTransient ActivationSignaling Pathway +9

BMPs functionally replace Klf4 and support efficient reprogramming of mouse fibroblasts by Oct4 alone

Jiekai Chen, Jing Liu, Jiaqi Yang, +7

Cell Research

Knockout MouseBiomedical ResearchMedicineMolecular BiologyStem Cell Research +4

The Primate-Specific Gene TMEM14B Marks Outer Radial Glia Cells and Promotes Cortical Expansion and Folding

Jing Liu, Wensu Liu, Lu Yang, +9

Cell stem cell

Glial BiologyNeuroregenerationDevelopmental BiologyEpendymaNeuroanatomy +9

Resolving Cell Fate Decisions during Somatic Cell Reprogramming by Single-Cell RNA-Seq

Lin Guo, Lihui Lin, Xiaoshan Wang, +19

Molecular Cell

Developmental BiologySingle Cell SequencingSingle-cell Rna-seqMedicineSomatic Cell Genetics +9

Lithium, an anti-psychotic drug, greatly enhances the generation of induced pluripotent stem cells

Quan Wang, Xinxiu Xu, Jun Li, +11

Cell Research

Epigenetic ChangeAdult Stem CellAnti-psychotic DrugStem Cell BiologyEpigenetics +21

Chromatin Accessibility Dynamics during Chemical Induction of Pluripotency

Shangtao Cao, Shengyong Yu, Dongwei Li, +19

Cell stem cell

ChromatinChromatin RemodelingNatural SciencesEpigenomicsMolecular Biology +6

Endoprotease-Mediated Intracellular Protein Delivery Using Nanocapsules

Anuradha Biswas, Kye‐Il Joo, Jing Liu, +5

ACS Nano

Tissue EngineeringNanomedicineUbiquitous Intracellular ProteaseCell-based Drug DeliveryIntracellular Delivery +9