Chang Han

Cyclooxygenase–2 Promotes Hepatocellular Carcinoma Cell Growth Through Akt Activation: Evidence for Akt Inhibition in Celecoxib–Induced Apoptosis

Jing Leng, Chang Han, Jake Demetris et al. · Hepatology · 2003 · 260 citations · Full text

Medicine, Oncology, Pharmacology +17

Docosahexaenoic acid induces autophagy through p53/AMPK/mTOR signaling and promotes apoptosis in human cancer cells harboring wild-type p53

Kaipeng Jing, Kyoungsub Song, Soyeon Shin et al. · Autophagy · 2011 · 197 citations · Full text

Life Sciences, Cell Biology, Oncology +17

Omega-3 polyunsaturated fatty acids inhibit hepatocellular carcinoma cell growth through blocking β-catenin and cyclooxygenase-2

Kyu Lim, Chang Han, Yifan Dai et al. · Molecular Cancer Therapeutics · 2009 · 187 citations · Full text

Medicine, Oncology, Pharmacology +13

Hedgehog Signaling Pathway Regulates Autophagy in Human Hepatocellular Carcinoma Cells

Ying Wang, Chang Han, Lu Lu et al. · Hepatology · 2013 · 155 citations

Life Sciences, Cell Biology, Oncology +17

The cyclooxygenase-2 inhibitor celecoxib blocks phosphorylation of Akt and induces apoptosis in human cholangiocarcinoma cells

Tong Wu, Jing Leng, Chang Han et al. · Molecular Cancer Therapeutics · 2004 · 146 citations · Full text

Life Sciences, Oncology, Pharmacology +17