Nanobody-based CAR T cells that target the tumor microenvironment inhibit the growth of solid tumors in immunocompetent mice

Yushu Joy Xie, Michael Dougan, Noor Jailkhani, +8

Proceedings of the National Academy of Sciences

Maternal imprinting at the H19–Igf2 locus maintains adult haematopoietic stem cell quiescence

Aparna Venkatraman, Xi He, Joanne L. Thorvaldsen, +15

Nature

H19–igf2 LocusChromatinCell LineageDevelopmental BiologyEpigenetic Regulation +12

Suppression of m6A reader Ythdf2 promotes hematopoietic stem cell expansion

Zhenrui Li, Pengxu Qian, Wanqing Shao, +28

Cell Research

Radiation OncologyHealth SciencesMedicineStem Cell MobilizationStem Cell Transplantation +7

The Dlk1-Gtl2 Locus Preserves LT-HSC Function by Inhibiting the PI3K-mTOR Pathway to Restrict Mitochondrial Metabolism

Pengxu Qian, Xi He, Ariel Paulson, +15

Cell stem cell

MitophagySignal TransductionMitochondrial FunctionPi3k-mtor PathwayOrganelle Dynamic +8

N-Cadherin-Expressing Bone and Marrow Stromal Progenitor Cells Maintain Reserve Hematopoietic Stem Cells

Meng Zhao, Tao Fang, Aparna Venkatraman, +10

Cell Reports

Overcoming Wnt–β-catenin dependent anticancer therapy resistance in leukaemia stem cells

John M. Perry, Tao Fang, Anuradha Roy, +33

Nature Cell Biology

Hematological MalignancyCell TherapyOncologyMedicineCancer Cell Biology +8

Aptamer selection and application in multivalent binding-based electrical impedance detection of inactivated H1N1 virus

Chenjun Bai, Zhangwei Lu, Hua Jiang, +12

Biosensors and Bioelectronics

Diagnostic VirologyEngineeringViral DiagnosticsSynthetic VirologyInactivated H1n1 Virus +8

Improved Antitumor Efficacy of Chimeric Antigen Receptor T Cells that Secrete Single-Domain Antibody Fragments

Yushu Joy Xie, Michael Dougan, Jessica R. Ingram, +4

Cancer Immunology Research

Chimeric Antigen ReceptorNanomedicineCar T CellsTumor ImmunologyCancer Immunosurveillance +11

Exosomal Transfer of Vasorin Expressed in Hepatocellular Carcinoma Cells Promotes Migration of Human Umbilical Vein Endothelial Cells

Aixue Huang, Jie Dong, Shaohua Li, +11

International Journal of Biological Sciences

Cancer Nanomedicines Stabilized by π-π Stacking between Heterodimeric Prodrugs Enable Exceptionally High Drug Loading Capacity and Safer Delivery of Drug Combinations

Hangxiang Wang, Jianmei Chen, Chang Xu, +8

Theranostics