Yanling Zhang

PI(3,5)P2 controls membrane trafficking by direct activation of mucolipin Ca2+ release channels in the endolysosome

Xian‐Ping Dong, Dongbiao Shen, Xiang Wang et al. · Nature Communications · 2010 · 627 citations · Full text

Protein Secretion, Signal Transduction, Molecular Physiology +13

Mutation of FIG4 causes neurodegeneration in the pale tremor mouse and patients with CMT4J

Clement Y. Chow, Yanling Zhang, James J. Dowling et al. · Nature · 2007 · 505 citations · Full text

Knockout Mouse, Genetic Disorder, Natural Sciences +8

VAC14 nucleates a protein complex essential for the acute interconversion of PI3P and PI(3,5)P2 in yeast and mouse

Natsuko Jin, Clement Y. Chow, Li Liu et al. · The EMBO Journal · 2008 · 262 citations · Full text

Acute Interconversion, Protein Function, Signal Transduction +8

In vivo, Pikfyve generates PI(3,5)P ₂ , which serves as both a signaling lipid and the major precursor for PI5P

Sergey N. Zolov, Dave Bridges, Yanling Zhang et al. · Proceedings of the National Academy of Sciences · 2012 · 232 citations · Full text

Loss of Vac14, a regulator of the signaling lipid phosphatidylinositol 3,5-bisphosphate, results in neurodegeneration in mice

Yanling Zhang, Sergey N. Zolov, Clement Y. Chow et al. · Proceedings of the National Academy of Sciences · 2007 · 227 citations · Full text

Cell Death, Cellular Physiology, Social Sciences +21