Dongbiao Shen

PI(3,5)P2 controls membrane trafficking by direct activation of mucolipin Ca2+ release channels in the endolysosome

Xian‐Ping Dong, Dongbiao Shen, Xiang Wang et al. · Nature Communications · 2010 · 627 citations · Full text

Protein Secretion, Signal Transduction, Molecular Physiology +13

TPC Proteins Are Phosphoinositide- Activated Sodium-Selective Ion Channels in Endosomes and Lysosomes

Xiang Wang, Xiaoli Zhang, Xian‐Ping Dong et al. · Cell · 2012 · 513 citations

Lipid storage disorders block lysosomal trafficking by inhibiting a TRP channel and lysosomal calcium release

Dongbiao Shen, Xiang Wang, Xinran Li et al. · Nature Communications · 2012 · 485 citations · Full text

Proteinlipid Interaction, Molecular Biology, Lipid Movement +16

TRP Channel Regulates EGFR Signaling in Hair Morphogenesis and Skin Barrier Formation

Xiping Cheng, Jie Jin, Lily Hu et al. · Cell · 2010 · 315 citations · Full text

Skin Development, Signal Transduction, Molecular Physiology +12

Activating Mutations of the TRPML1 Channel Revealed by Proline-scanning Mutagenesis

Xian‐Ping Dong, Xiang Wang, Dongbiao Shen et al. · Journal of Biological Chemistry · 2009 · 130 citations · Full text

Trpml1 Channel, Mucolipin Trp, Molecular Biology +18