Jian‐Guo Zhang

The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism

James M. Murphy, Peter E. Czabotar, Joanne M. Hildebrand et al. · Immunity · 2013 · 1.2K citations · Full text

Protein Function, Signal Transduction, Medicine +14

SOCS3 negatively regulates IL-6 signaling in vivo

Ben A. Croker, Danielle L. Krebs, Jian‐Guo Zhang et al. · Nature Immunology · 2003 · 833 citations

Inflammation, Cytokine, Autoimmune Disease +7

The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation

Jian‐Guo Zhang, Alison Farley, Sandra E. Nicholson et al. · Proceedings of the National Academy of Sciences · 1999 · 630 citations · Full text

Immunology, Elongins B, Signaling Pathway +17

Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp130

Sandra E. Nicholson, David P. De Souza, Louis Fabri et al. · Proceedings of the National Academy of Sciences · 2000 · 463 citations

Impact of anemia on hospitalization and mortality in older adults

Bruce F. Culleton, Braden Manns, Jian‐Guo Zhang et al. · Blood · 2006 · 453 citations · Full text