The TLR4 antagonist Eritoran protects mice from lethal influenza infection

Kari Ann Shirey, Wendy Lai, Alison Scott, +13

Nature

InflammationTlr4 Antagonist EritoranInnate Immune SystemImmunologyAntiviral Response +3

5,6-Dimethylxanthenone-4-acetic Acid (DMXAA) Activates Stimulator of Interferon Gene (STING)-dependent Innate Immune Pathways and Is Regulated by Mitochondrial Membrane Potential

Daniel Prantner, Darren J. Perkins, Wendy Lai, +4

Journal of Biological Chemistry

InflammationCytokineInnate Immune SystemImmunologyImmune Regulation +7

Novel strategies for targeting innate immune responses to influenza

Kari Ann Shirey, Wendy Lai, Mira C. Patel, +14

Mucosal Immunology

VaccinationCross-protectionNovel StrategiesInnate Immune SystemImmunology +5

Role of the lipoxygenase pathway in RSV-induced alternatively activated macrophages leading to resolution of lung pathology

Kari Ann Shirey, Wendy Lai, Lioubov M. Pletneva, +4

Mucosal Immunology

AsthmaInflammationLipoxygenase PathwayInflammatory Lung DiseaseLung Inflammation +8

Autocrine–paracrine prostaglandin E2 signaling restricts TLR4 internalization and TRIF signaling

Darren J. Perkins, Katharina Richard, Anne-Marie Hansen, +4

Nature Immunology

Transcriptional RegulationSignal TransductionSignaling PathwayMolecular PathwayAutocrine–paracrine Prostaglandin E2 +4

Influenza “Trains” the Host for Enhanced Susceptibility to Secondary Bacterial Infection

Kari Ann Shirey, Darren J. Perkins, Wendy Lai, +5

mBio

A Decoy Peptide that Disrupts TIRAP Recruitment to TLRs Is Protective in a Murine Model of Influenza

Wenji Piao, Kari Ann Shirey, Lisa W. Ru, +7

Cell Reports

Gene transfection and expression in resting and activated murine CD4 T cell subsets

Wendy Lai, Cheong‐Hee Chang, Donna L. Färber

Journal of Immunological Methods

Lymphocyte DevelopmentAdaptive Immune SystemT-regulatory CellImmunologyAntigen Processing +5

Early or Late Bacterial Lung Infection Increases Mortality After Traumatic Brain Injury in Male Mice and Chronically Impairs Monocyte Innate Immune Function

Sarah J. Doran, Rebecca J. Henry, Kari Ann Shirey, +7

Critical Care Medicine

Transcriptional Control of Rapid Recall by Memory CD4 T Cells

Wendy Lai, Minjun Yu, Min-Nung Huang, +3

The Journal of Immunology