Darren J. Perkins

TLR4/MyD88/PI3K interactions regulate TLR4 signaling

Michelle Laird, Sang Hoon Rhee, Darren J. Perkins et al. · Journal of Leukocyte Biology · 2009 · 336 citations · Full text

Life Sciences, Cell Biology, Immunology +17

5,6-Dimethylxanthenone-4-acetic Acid (DMXAA) Activates Stimulator of Interferon Gene (STING)-dependent Innate Immune Pathways and Is Regulated by Mitochondrial Membrane Potential

Daniel Prantner, Darren J. Perkins, Wendy Lai et al. · Journal of Biological Chemistry · 2012 · 215 citations · Full text

Life Sciences, Immunology, Pharmacology +17

CD14 dependence of TLR4 endocytosis and TRIF signaling displays ligand specificity and is dissociable in endotoxin tolerance

Rajesh Rajaiah, Darren J. Perkins, Derek D.C. Ireland et al. · Proceedings of the National Academy of Sciences · 2015 · 144 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

Characterization of Two Evolutionarily Conserved, Alternatively Spliced Nuclear Phosphoproteins, NFAR-1 and -2, That Function in mRNA Processing and Interact with the Double-stranded RNA-dependent Protein Kinase, PKR

Laura R. Saunders, Darren J. Perkins, Siddharth Balachandran et al. · Journal of Biological Chemistry · 2001 · 124 citations · Full text

Life Sciences, Genetics, Molecular Biology +13

Transcriptional Regulation of Murine IL-33 by TLR and Non-TLR Agonists

Swamy K. Polumuri, Gift Gunaraj Jayakar, Kari Ann Shirey et al. · The Journal of Immunology · 2012 · 114 citations · Full text

Life Sciences, Immunology, Molecular Biology +17