Darren J. Perkins

TLR4/MyD88/PI3K interactions regulate TLR4 signaling

Michelle Laird, Sang Hoon Rhee, Darren J. Perkins et al. · Journal of Leukocyte Biology · 2009 · 333 citations · Full text

Innate Immune System, Immunology, Cell Death +16

5,6-Dimethylxanthenone-4-acetic Acid (DMXAA) Activates Stimulator of Interferon Gene (STING)-dependent Innate Immune Pathways and Is Regulated by Mitochondrial Membrane Potential

Daniel Prantner, Darren J. Perkins, Wendy Lai et al. · Journal of Biological Chemistry · 2012 · 208 citations · Full text

Inflammation, Cytokine, Innate Immune System +9

CD14 dependence of TLR4 endocytosis and TRIF signaling displays ligand specificity and is dissociable in endotoxin tolerance

Rajesh Rajaiah, Darren J. Perkins, Derek D.C. Ireland et al. · Proceedings of the National Academy of Sciences · 2015 · 140 citations · Full text

Characterization of Two Evolutionarily Conserved, Alternatively Spliced Nuclear Phosphoproteins, NFAR-1 and -2, That Function in mRNA Processing and Interact with the Double-stranded RNA-dependent Protein Kinase, PKR

Laura R. Saunders, Darren J. Perkins, Siddharth Balachandran et al. · Journal of Biological Chemistry · 2001 · 122 citations · Full text

Transcriptional Regulation of Murine IL-33 by TLR and Non-TLR Agonists

Swamy K. Polumuri, Gift Gunaraj Jayakar, Kari Ann Shirey et al. · The Journal of Immunology · 2012 · 112 citations · Full text