RAD001 Inhibits Human Ovarian Cancer Cell Proliferation, Enhances Cisplatin-Induced Apoptosis, and Prolongs Survival in an Ovarian Cancer Model

Seiji Mabuchi, Deborah A. Altomare, Mitchell Cheung, +6

Clinical Cancer Research

Individual Overexpression of Five Subunits of Human Translation Initiation Factor eIF3 Promotes Malignant Transformation of Immortal Fibroblast Cells

Lili Zhang, Xiaoyu Pan, John W.B. Hershey

Journal of Biological Chemistry

Endothelium-targeted overexpression of heat shock protein 27 ameliorates blood–brain barrier disruption after ischemic brain injury

Yejie Shi, Xiaoyan Jiang, Lili Zhang, +9

Proceedings of the National Academy of Sciences

Endothelial CellsCell DeathCytoskeletonBiomedical EngineeringActin Polymerization +19

Peroxiredoxin-2 Protects against 6-Hydroxydopamine-Induced Dopaminergic Neurodegeneration via Attenuation of the Apoptosis Signal-Regulating Kinase (ASK1) Signaling Cascade

Xiaoming Hu, Zhongfang Weng, Charleen T. Chu, +8

Journal of Neuroscience

ApoptosisCell DeathAntioxidant EnzymesRedox BiologyOxidative Stress +16

Mitochondrial DNA oxidation induces imbalanced activity of NLRP3/NLRP6 inflammasomes by activation of caspase-8 and BRCC36 in dry eye

Wei Chi, Xia Hua, Xin Chen, +11

Journal of Autoimmunity

InflammationReductive StressMitochondrial FunctionDry EyeImmunology +9

Absence of the inflammasome adaptor ASC reduces hypoxia-induced pulmonary hypertension in mice

Fadila Telarevic Cero, Vigdis Hillestad, Ivar Sjaastad, +12

American Journal of Physiology-Lung Cellular and Molecular Physiology

Inflammatory Lung DiseaseLung InflammationRight VentricularApoptosisImmunology +22

Transgenic Overexpression of Peroxiredoxin-2 Attenuates Ischemic Neuronal Injury <i>Via</i> Suppression of a Redox-Sensitive Pro-Death Signaling Pathway

Yu Gan, Xunming Ji, Xiaoming Hu, +9

Antioxidants and Redox Signaling

Activated TNF-α/NF-κB signaling via down-regulation of Fas-associated factor 1 in asbestos-induced mesotheliomas from <i>Arf</i> knockout mice

Deborah A. Altomare, Craig W. Menges, Jianming Pei, +5

Proceedings of the National Academy of Sciences

Development of Upconversion Luminescent Probe for Ratiometric Sensing and Bioimaging of Hydrogen Sulfide

Shujuan Liu, Lili Zhang, Tianshe Yang, +9

ACS Applied Materials & Interfaces

Upconversion Luminescent ProbeEngineeringRatiometric SensingChemistryChemical Engineering +15

Losses of Both Products of the Cdkn2a/Arf Locus Contribute to Asbestos-Induced Mesothelioma Development and Cooperate to Accelerate Tumorigenesis

Deborah A. Altomare, Craig W. Menges, Jinfei Xu, +9

PLoS ONE