Concepedia

Mitochondrial DNA oxidation induces imbalanced activity of NLRP3/NLRP6 inflammasomes by activation of caspase-8 and BRCC36 in dry eye

Wei Chi, Xia Hua, Xin Chen, Fang Bian, Xiaoyong Yuan, Lili Zhang, Xiaoran Wang, Ding Chen, Ruzhi Deng, Zhijie Li,

Journal of Autoimmunity · 2017 · 112 citations · 29 references

DOI

Concepts

References

29

A role for mitochondria in NLRP3 inflammasome activation

Rongbin Zhou, Amir S. Yazdi, Philippe Menu et al. · Nature · 2010 · 5.4K citations

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Upregulated NLRP3 Inflammasome Activation in Patients With Type 2 Diabetes

Hyemi Lee, Jwa-Jin Kim, Hyun Jin Kim et al. · Diabetes · 2012 · 738 citations · Full text

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Pro- and anti-inflammatory forms of interleukin-1 in the tear fluid and conjunctiva of patients with dry-eye disease.

Abraham Solomon, Dilek Dursun, Zhihong Liu et al. · PubMed · 2001 · 729 citations

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Deubiquitination of NLRP3 by BRCC3 Critically Regulates Inflammasome Activity

Bénédicte F. Py, Mi-Sung Kim, Helin Vakifahmetoglu-Norberg et al. · Molecular Cell · 2012 · 707 citations · Full text

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The Relationship between Habitual Patient-Reported Symptoms and Clinical Signs among Patients with Dry Eye of Varying Severity

Carolyn G. Begley, Robin L. Chalmers, Linda Abetz et al. · Investigative Ophthalmology & Visual Science · 2003 · 424 citations

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