Deborah A. Altomare

Molecular alterations of the <i>AKT</i>2 oncogene in ovarian and breast carcinomas

Alfonso Bellacosa, Daniela de Feo, Andrew K. Godwin et al. · International Journal of Cancer · 1995 · 836 citations

Medicine, Genetics, Oncology +14

Amplification of AKT2 in human pancreatic cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA.

Jin Q. Cheng, Bruce Ruggeri, Willemijn M. Klein et al. · Proceedings of the National Academy of Sciences · 1996 · 793 citations

Medicine, Molecular Biology, Oncology +17

AKT and mTOR phosphorylation is frequently detected in ovarian cancer and can be targeted to disrupt ovarian tumor cell growth

Deborah A. Altomare, Hui Qin Wang, Kristine L. Skele et al. · Oncogene · 2004 · 420 citations

Medicine, Cancer Biology, Oncology +16

p16 alterations and deletion mapping of 9p21-p22 in malignant mesothelioma.

Jin Cheng, S C Jhanwar, Willemijn M. Klein et al. · PubMed · 1994 · 325 citations

Veterinary Medicine, Genetics, Oncology +10

RAD001 Inhibits Human Ovarian Cancer Cell Proliferation, Enhances Cisplatin-Induced Apoptosis, and Prolongs Survival in an Ovarian Cancer Model

Seiji Mabuchi, Deborah A. Altomare, Mitchell Cheung et al. · Clinical Cancer Research · 2007 · 233 citations · Full text

Medicine, Oncology, Pharmacology +14