Palladium-triggered deprotection chemistry for protein activation in living cells

Jie Li, Juntao Yu, Jingyi Zhao, +8

Nature Chemistry

Protein FunctionBiochemistryNatural SciencesPalladium-triggered Deprotection ChemistryBioconjugation +3

Strain-Release Heteroatom Functionalization: Development, Scope, and Stereospecificity

Justin M. Lopchuk, Kasper Fjelbye, Yu Kawamata, +21

Journal of the American Chemical Society

Time-resolved protein activation by proximal decaging in living systems

Jie Wang, Yuan Liu, Yanjun Liu, +7

Nature

Protein SecretionProtein FunctionProtein FoldingTime-resolved Protein ActivationNatural Sciences +3

SAR1B senses leucine levels to regulate mTORC1 signalling

Jie Chen, Yuhui Ou, Rong Luo, +7

Nature

Signal TransductionMolecular PhysiologyG Protein-coupled ReceptorLeucine LevelsMedicine +3

Ligand-Free Palladium-Mediated Site-Specific Protein Labeling Inside Gram-Negative Bacterial Pathogens

Jie Li, Shixian Lin, Jie Wang, +5

Journal of the American Chemical Society

Optimized Tetrazine Derivatives for Rapid Bioorthogonal Decaging in Living Cells

Xinyuan Fan, Yun Ge, Feng Lin, +9

Angewandte Chemie International Edition

Palladium-Triggered Chemical Rescue of Intracellular Proteins via Genetically Encoded Allene-Caged Tyrosine

Jie Wang, Siqi Zheng, Yanjun Liu, +7

Journal of the American Chemical Society

Src KinaseProtein AssemblyMolecular BiologyPalladium-triggered Chemical RescueChemical Biology +14

Copper-Triggered Bioorthogonal Cleavage Reactions for Reversible Protein and Cell Surface Modifications

Xin Wang, Yanjun Liu, Xinyuan Fan, +7

Journal of the American Chemical Society

Chemical Remodeling of Cell‐Surface Sialic Acids through a Palladium‐Triggered Bioorthogonal Elimination Reaction

Jie Wang, Bo Cheng, Jie Li, +4

Angewandte Chemie International Edition

Homeostasis of branched-chain amino acids is critical for the activity of TOR signaling in Arabidopsis

Pengfei Cao, Sang‐Jin Kim, Anqi Xing, +6

eLife

GeneticsMolecular BiologyCytoskeletonPlant Molecular BiologyBiosynthesis +17