Jie Chen

Metformin extends C. elegans lifespan through lysosomal pathway

Jie Chen, Yuhui Ou, Yi Li et al. · eLife · 2017 · 207 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

SAR1B senses leucine levels to regulate mTORC1 signalling

Jie Chen, Yuhui Ou, Rong Luo et al. · Nature · 2021 · 203 citations

Life Sciences, Neuroscience, Cell Signaling +5

KLHL22 activates amino-acid-dependent mTORC1 signalling to promote tumorigenesis and ageing

Jie Chen, Yuhui Ou, Yanyan Yang et al. · Nature · 2018 · 128 citations

Life Sciences, Molecular Biology, Oncology +12

Multiple sequence alignment-based RNA language model and its application to structural inference

Yikun Zhang, Mei Lang, Jiuhong Jiang et al. · Nucleic Acids Research · 2023 · 98 citations · Full text

Life Sciences, Bioinformatics, Biology +11

E3 ligase RNF167 and deubiquitinase STAMBPL1 modulate mTOR and cancer progression

Dong Wang, Chenchen Xu, Wenyu Yang et al. · Molecular Cell · 2022 · 80 citations

Medicine, Cancer Biology, Molecular Biology +13