Lu Chen

Autophagy inhibition mediated by MCOLN1/TRPML1 suppresses cancer metastasis via regulating a ROS-driven TP53/p53 pathway

Yanhong Xing, Xiangqing Wei, Yucheng Liu et al. · Autophagy · 2021 · 142 citations · Full text

Medicine, Cancer Biology, Oncology +17

Exosomes derived from GDNF-modified human adipose mesenchymal stem cells ameliorate peritubular capillary loss in tubulointerstitial fibrosis by activating the SIRT1/eNOS signaling pathway

Lu Chen, Yanping Wang, Shulin Li et al. · Theranostics · 2020 · 139 citations · Full text

Medicine, Cell Biology, Nephrology +16

Blunting TRPML1 channels protects myocardial ischemia/reperfusion injury by restoring impaired cardiomyocyte autophagy

Yanhong Xing, Zhongheng Sui, Yucheng Liu et al. · Basic Research in Cardiology · 2022 · 106 citations

Life Sciences, Cardiology, Cell Biology +15

Pellino1 regulates neuropathic pain as well as microglial activation through the regulation of MAPK/NF-κB signaling in the spinal cord

Lijuan Wang, Yin Cui, Tianya Liu et al. · Journal of Neuroinflammation · 2020 · 91 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

MCOLN1/TRPML1 finely controls oncogenic autophagy in cancer by mediating zinc influx

Jiansong Qi, Yanhong Xing, Yucheng Liu et al. · Autophagy · 2021 · 73 citations · Full text

Life Sciences, Cell Biology, Oncology +17