Genomic Analysis of Non- <i>NF2</i> Meningiomas Reveals Mutations in <i>TRAF7</i> , <i>KLF4</i> , <i>AKT1</i> , and <i>SMO</i>

Victoria Clark, E. Zeynep Erson‐Omay, Akdes Serin, +42

Science

Synthesis, Structure–Activity Relationships, and in Vivo Efficacy of the Novel Potent and Selective Anaplastic Lymphoma Kinase (ALK) Inhibitor 5-Chloro-<i>N</i>2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)-<i>N</i>4-(2-(isopropylsulfonyl)phenyl)pyrimidine-2,4-diamine (LDK378) Currently in Phase 1 and Phase 2 Clinical Trials

Thomas H. Marsilje, Wei Pei, Bei Chen, +37

Journal of Medicinal Chemistry

Chemoprevention StrategyPharmacotherapyStructure–activity RelationshipsPharmaceutical ChemistryTumor Biology +19

Integrated genomic characterization of IDH1-mutant glioma malignant progression

Hanwen Bai, Akdes Serin Harmancı, E. Zeynep Erson‐Omay, +31

Nature Genetics

Tumor HeterogeneityCancer GenomicsCancer GeneticsSystems BiologyMedicine +3

Multiple Signal Transduction Pathways Link Na+/K+-ATPase to Growth-related Genes in Cardiac Myocytes

P. A. Kometiani, Jie Li, Luigi Gnudi, +3

Journal of Biological Chemistry

Inhibition of Autophagy by 3-MA Enhances the Effect of 5-FU-Induced Apoptosis in Colon Cancer Cells

Jie Li, Ni Hou, Ahmad Faried, +3

Annals of Surgical Oncology

3-Ma EnhancesMitophagyCell AutophagyMedicineColon Cancer Cells +10

PRL-3 and PRL-1 promote cell migration, invasion, and metastasis.

Qi Zeng, Jingming Dong, Ke Guo, +6

PubMed

Cell ProliferationCellular PhysiologyTumor BiologyInactive Prl-3 MutantSignaling Pathway +14

Emerging Role for Autophagy in the Removal of Aggresomes in Schwann Cells

Jenny Fortun, William A. Dunn, Shale Joy, +2

Journal of Neuroscience

MitophagyImmunologyProteasomeSchwann CellsCytoskeleton +22

The m6A demethylase FTO promotes the growth of lung cancer cells by regulating the m6A level of USP7 mRNA

Jie Li, Yi Han, Hongmei Zhang, +5

Biochemical and Biophysical Research Communications

Overexpression of c-erbB-2/neu in breast cancer cells confers increased resistance to Taxol via mdr-1-independent mechanisms.

Dihua Yu, Bolin Liu, Ming Tan, +3

PubMed

Enhancement of proteasomal function protects against cardiac proteinopathy and ischemia/reperfusion injury in mice

Jie Li, K Horák, Huabo Su, +3

Journal of Clinical Investigation

Heart FailureImmunologyProteasomeCell DeathCardiovascular Function +24