Inhibition of Autophagy by 3-MA Enhances the Effect of 5-FU-Induced Apoptosis in Colon Cancer Cells

Bcl-2 Antiapoptotic Proteins Inhibit Beclin 1-Dependent Autophagy

Sophie Pattingre, Amina Tassa, Xueping Qu et al. · Cell · 2005 · 3.5K citations · Full text

Life Sciences, Biochemistry, Cell Biology +8

Induction of autophagy and inhibition of tumorigenesis by beclin 1

Xiao Huan Liang, Saadiya Jackson, Matthew Seaman et al. · Nature · 1999 · 3.3K citations

Life Sciences, Cancer Biology, Cell Biology +12

Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: a multicentre randomised trial

J-Y Douillard, David Cunningham, AD Roth et al. · The Lancet · 2000 · 3.3K citations

Medicine, Oncology, Pharmacology +13

Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene

Xueping Qu, Jie Yu, Govind Bhagat et al. · Journal of Clinical Investigation · 2003 · 2.2K citations · Full text

Life Sciences, Genetics, Oncology +15

Phase III Multicenter Randomized Trial of Oxaliplatin Added to Chronomodulated Fluorouracil–Leucovorin as First-Line Treatment of Metastatic Colorectal Cancer

Sylvie Giacchetti, B Perpoint, Rachid Zidani et al. · Journal of Clinical Oncology · 2000 · 1.4K citations

Medicine, Oncology, Pharmacology +14